Clerodendrum Glandulosum Lindl.: A Review of Ethnopharmacology, Pharmacological Potentials, and their Mechanism of Action.

Autor: Khound P; Life Sciences Division, Institute of Advanced Study in Science & Technology (IASST), Vigyan Path, Paschim Boragaon, Guwahati, 781035, India.; Department of Zoology, Gauhati University, Jalukbari, Guwahati, 781014, India., Devi R; Life Sciences Division, Institute of Advanced Study in Science & Technology (IASST), Vigyan Path, Paschim Boragaon, Guwahati, 781035, India.; Department of Zoology, Gauhati University, Jalukbari, Guwahati, 781014, India.
Jazyk: angličtina
Zdroj: Chemistry & biodiversity [Chem Biodivers] 2024 Apr; Vol. 21 (4), pp. e202302121. Date of Electronic Publication: 2024 Mar 11.
DOI: 10.1002/cbdv.202302121
Abstrakt: Clerodendrum glandulosum Lindl. is popularly known for its traditional herbal remedies and therapeutic properties among the people of Northeast Indian communities, as well as Chinese traditional medicine. For the myriad pharmacological properties, viz., anti-hypertensive, hypolipidemic, hepatoprotective, anti-inflammatory, and neuroprotective, planting this species in kitchen gardens is a common practice to treat various ailments, especially hypertension, diabetes, and other metabolic complications. Different phytochemicals, representing the diverse classes of secondary metabolites comprising physiological and phytopharmaceutical significance, have been reported from C. glandulosum. Compounds with terpenoids, steroids, and phenolics are in demand in the pharmaceutical industry. An overview of the mechanism of action of the prominent compounds has also been collated for future research on C. glandulosum-based therapeutics. Current information focuses on this important medicinal plant's ethnomedicinal use, phytochemistry, pharmacology, associated mechanisms, and toxicology. This review will help explore this potential medicinal plant, which can pave the path for its application in the pharmaceutical industry.
(© 2024 Wiley‐VHCA AG, Zurich, Switzerland.)
Databáze: MEDLINE
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