Leucaena leucocephala toxicity in Brazilian horses.

Autor: Machado M; Plataforma de Investigación en Salud Animal (PSA), Instituto Nacional de Investigación Agropecuaria (INIA), Estación Experimental del Norte, Tacuarembó, Uruguay. Electronic address: mmachado@inia.org.uy., Queiroz-Machado CRR; Centro Universitario Regional (CENUR) Noreste, Universidad de la República (UdelaR), Tacuarembó, Uruguay., Gardner DR; Poisonous Plant Research Laboratory, Agriculture Research Service, United States Department of Agriculture, Logan, USA., Castro MB; Veterinary Pathology Laboratory, College of Agronomy and Veterinary Medicine, University of Brasília, Brasilia, Distrito Federal, Brazil., Câmara ACL; Large Animal Veterinary Teaching Hospital, College of Agronomy and Veterinary Medicine, University of Brasília, Brasilia, Distrito Federal, Brazil., Pimentel LA; Setor de Patologia Veterinária, Hospital Universitário de Medicina Veterinária, Universidade Federal do Recôncavo da Bahia (UFRB), Cruz das Almas, Bahia, Brazil., Galiza GJN; Programa de Pós-graduação em Ciência e Saúde Animal, Universidade Federal de Campina Grande (UFCG), Patos, Paraíba, Brazil., Riet-Correa F; Programa de Pós-graduação em Ciências Animais nos Trópicos, Universidade Federal da Bahia (UFBA), Salvador, Bahia, Brazil.
Jazyk: angličtina
Zdroj: Toxicon : official journal of the International Society on Toxinology [Toxicon] 2024 Mar; Vol. 240, pp. 107655. Date of Electronic Publication: 2024 Feb 19.
DOI: 10.1016/j.toxicon.2024.107655
Abstrakt: Leucaena leucocephala poisoning is reported in horses in different Brazilian regions. The poisoning occurred one month after the horses were introduced into paddocks invaded by the plant or after 10 days of consuming cut Leucaena administered as the only food. Affected horses showed moderate to severe hair loss on the mane and tail, orthokeratotic hyperkeratosis with marked follicular telogenization, and hyperplasia of thyroid follicular cells. Mimosin concentration in leaves (5.5 mg/g) was determined by a new HLPC-UV method which is also reported.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024. Published by Elsevier Ltd.)
Databáze: MEDLINE
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