| Autor: |
Santos KSDC; Universidade Tiradentes, Departamento de Medicina, Aracaju, Sergipe, Brazil., Brito GMG; Universidade Tiradentes, Departamento de Medicina, Aracaju, Sergipe, Brazil., Melo EV; Universidade Federal de Sergipe, Departamento de Medicina, Aracaju, Sergipe, Brazil., Sousa ACS; Universidade Federal de Sergipe, Departamento de Medicina, Aracaju, Sergipe, Brazil.; Universidade Federal de Sergipe, Programa de Pós-Graduação em Ciências da Saúde, Aracaju, Sergipe, Brazil.; Rede D'Or São Luiz, Clínica e Hospital São Lucas, Aracaju, Sergipe, Brazil.; Universidade Federal de Sergipe, Hospital Universitário, Divisão de Cardiologia, Aracaju, Sergipe, Brazil., Martins-Filho PR; Universidade Federal de Sergipe, Programa de Pós-Graduação em Ciências da Saúde, Aracaju, Sergipe, Brazil.; Universidade Federal de Sergipe, Hospital Universitário, Laboratório de Patologia Investigativa, Aracaju, Sergipe, Brazil., Campos MDSB; Universidade Tiradentes, Departamento de Medicina, Aracaju, Sergipe, Brazil.; Universidade Federal de Sergipe, Programa de Pós-Graduação em Ciências da Saúde, Aracaju, Sergipe, Brazil.; Rede D'Or São Luiz, Clínica e Hospital São Lucas, Aracaju, Sergipe, Brazil.; Universidade Federal de Sergipe, Hospital Universitário, Divisão de Cardiologia, Aracaju, Sergipe, Brazil. |
| Abstrakt: |
The varied clinical presentations of SARS-CoV-2 infection have raised concerns about long-term consequences, especially "long-COVID" or "post-COVID-19 syndrome." In this context, the cardiorespiratory optimal point (COP) within the Cardiopulmonary Exercise Test (CPET) emerges as a crucial metric for evaluating functional capacities and detecting cardiovascular and pulmonary anomalies post-COVID-19. This study aimed to assess COP values among post-COVID-19 patients and categorized them based on the initial severity of their disease. In this cross-sectional study conducted in the Northeast Brazil, 80 patients (26 females and 54 males) previously infected with SARS-CoV-2 underwent CPET. We clinically stratified patients into mild, moderate, or severe COVID-19 categories and assessed COP values and other cardiorespiratory metrics. We found differences in the predicted COP between patients with mild and severe COVID-19 (p=0.042). Additionally, patients with moderate and severe COVID-19 record had an average COP value exceeding 22. Other parameters, including respiratory exchange ratio, heart rate, and oxygen uptake efficiency slope, did not differ across the groups. Patients with a history of severe COVID-19 showed altered COP values, suggesting potential discrepancies in cardiovascular and respiratory system integration. The outcomes emphasize the importance of continuous monitoring and assessment of the cardiorespiratory domain for post-COVID-19 patients. Further research is needed to understand the relationship between elevated COP in post-severe COVID-19 and its long-term prognostic implications. |
