Trajectory of health-related quality of life in parents of children treated with epilepsy surgery versus medical therapy.

Autor: Widjaja E; Department of Medical Imaging, Ann and Robert H. Lurie Children's Hospital, 225 E Chicago Ave, Chicago, IL, 60611, USA. ewidjaja@luriechildrens.org.; Neuroscience and Mental Health Program, The Hospital for Sick Children, Toronto, ON, Canada. ewidjaja@luriechildrens.org., Puka K; Department of Epidemiology and Biostatistics, Western University, London, ON, Canada., Smith ML; Department of Psychology, University of Toronto Mississauga, Mississauga, ON, Canada.
Jazyk: angličtina
Zdroj: Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation [Qual Life Res] 2024 May; Vol. 33 (5), pp. 1297-1305. Date of Electronic Publication: 2024 Feb 21.
DOI: 10.1007/s11136-024-03607-1
Abstrakt: Purpose: Child health-related quality of life (HRQOL) has been shown to improve after epilepsy surgery and is linked to parent HRQOL. We postulated that the HRQOL of parents whose children underwent epilepsy surgery would improve over two years compared to those treated with medical therapy. The aim of the study was to evaluate the trajectory of HRQOL of parents whose children received treatment with epilepsy surgery or medical therapy over two years.
Methods: This multi-center study recruited parents whose children were evaluated for epilepsy surgery. Parents completed measures of care-related QOL (CarerQOL) at the time of their children's surgical evaluation, 6 months, 1 year, and 2 years later. Additional measures included parent anxiety and depression, satisfaction with family relationships, family resources and demands, and child clinical variables. A linear mixed model was used to compare the trajectories of parent HRQOL of surgical and medical patients, adjusting for baseline clinical, parent, and family characteristics.
Results: There were 111 children treated with surgery and 154 with medical therapy. The trajectory of parent HRQOL was similar among parents of surgical and medical patients over the two-year follow-up. However, HRQOL of parents of surgical patients was 3.0 points higher (95%CI - 0.1, 6.1) across the follow-up period compared to parents of medical patients. Parents of seizure-free children reported 2.3 points (95%CI 0.2, 4.4) higher HRQOL relative to parents of non-seizure-free children across the two-year follow-up.
Conclusion: Parent HRQOL did not improve after their children were treated with epilepsy surgery, possibly related to ongoing comorbidities in children.
(© 2024. The Author(s), under exclusive licence to Springer Nature Switzerland AG.)
Databáze: MEDLINE
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