Adult Presentation of Cutaneous Langerhans Cell Histiocytosis: 18 F-FDG PET/CT Detection of Systemic Disease.

Autor: Robinson E, Nawwar A, Searle J, Lyburn I
Jazyk: angličtina
Zdroj: Clinical nuclear medicine [Clin Nucl Med] 2024 Apr 01; Vol. 49 (4), pp. 333-334. Date of Electronic Publication: 2024 Feb 08.
DOI: 10.1097/RLU.0000000000005109
Abstrakt: Abstract: Langerhans cell histiocytosis (LCH) is a rare hematological disease, more common in pediatric populations. A 26-year-old man with biopsy-proven cutaneous LCH underwent 18 F-FDG PET/CT systemic staging. 18 F-FDG PET/CT highlighted multiple sites of avid cutaneous disease within the natal cleft. Additional characteristic cystic lung disease was seen on the CT component and focal uptake in the pituitary stalk/hypothalamic region noted, a common but occult site of disease in this patient. Because of the rarity of adult-onset cutaneous LCH, guidance on management and staging is lacking. 18 F-FDG PET/CT is critical to baseline evaluation of systemic disease, as illustrated here.
Competing Interests: Conflicts of interest and sources of funding: none declared.
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Databáze: MEDLINE