Transition from pediatric to adult care in patients with Turner syndrome in Italy: a consensus statement by the TRAMITI project.

Autor: Aversa T; Department of Human Pathology of Adulthood and Childhood, University of Messina, Messina, Italy.; Pediatric Unit, University Hospital 'G. Martino', Via Consolare Valeria N. 1, 98124, Messina, Italy., De Sanctis L; Pediatric Endocrinology, Regina Margherita Children Hospital, Turin, Italy.; Department of Public Health and Pediatric Sciences, University of Turin, Turin, Italy., Faienza MF; Department of Precision and Regenerative Medicine and Ionian Area, University of Bari 'Aldo Moro', 70124, Bari, Italy., Gambineri A; Division of Endocrinology and Diabetes Prevention and Care, Department of Medical and Surgical Sciences (DIMEC), IRCCS Azienda Ospedaliero - Universitaria di Bologna, Bologna, Italy., Balducci A; Pediatric Cardiology and Adult Congenital Heart Disease Program, Department of Cardio - Thoracic and Vascular Medicine, IRCCS Azienda Ospedaliero - Universitaria Di Bologna, Bologna, Italy., D'Aprile R; Department of Women's and Children's Health, University of Padua, Padua, Italy.; A.Fa.D.O.C. Association OdV, Vicenza, Italy., Di Somma C; Unit of Endocrinology, AOU Federico II, Naples, Italy., Giavoli C; Endocrinology Unit, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milan, Italy., Grossi A; Endocrine Pathology of Chronic and Post-Tumor Diseases Unit, 'Bambino Gesù' Pediatric Hospital, Rome, Italy., Meriggiola MC; Division of Gynecology and Physiopathology of Reproduction, Department of Medical and Surgical Sciences (DIMEC), IRCCS Azienda Ospedaliero - Universitaria di Bologna, Bologna, Italy., Profka E; Endocrinology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Salerno M; Pediatric Section, Department of Translational Medical Sciences, University of Naples Federico II, Naples, Italy., Stagi S; Health Sciences Department, University of Florence, Florence, Italy.; Meyer Children's Hospital IRCCS, Florence, Italy., Scarano E; Pediatric Unit, IRCCS Azienda Ospedaliero - Universitaria di Bologna, Bologna, Italy., Zatelli MC; Section of Endocrinology, Geriatrics and Internal Medicine, Department of Medical Sciences, University of Ferrara, Ferrara, Italy., Wasniewska M; Department of Human Pathology of Adulthood and Childhood, University of Messina, Messina, Italy. malgorzata.wasniewska@unime.it.; Pediatric Unit, University Hospital 'G. Martino', Via Consolare Valeria N. 1, 98124, Messina, Italy. malgorzata.wasniewska@unime.it.
Jazyk: angličtina
Zdroj: Journal of endocrinological investigation [J Endocrinol Invest] 2024 Jul; Vol. 47 (7), pp. 1585-1598. Date of Electronic Publication: 2024 Feb 20.
DOI: 10.1007/s40618-024-02315-4
Abstrakt: Purpose: Transition from pediatric to adult care is associated with significant challenges in patients with Turner syndrome (TS). The objective of the TRansition Age Management In Turner syndrome in Italy (TRAMITI) project was to improve the care provided to patients with TS by harnessing the knowledge and expertise of various Italian centers through a Delphi-like consensus process.
Methods: A panel of 15 physicians and 1 psychologist discussed 4 key domains: transition and referral, sexual and bone health and oncological risks, social and psychological aspects and systemic and metabolic disorders.
Results: A total of 41 consensus statements were drafted. The transition from pediatric to adult care is a critical period for patients with TS, necessitating tailored approaches and early disclosure of the diagnosis to promote self-reliance and healthcare autonomy. Fertility preservation and bone health strategies are recommended to mitigate long-term complications, and psychiatric evaluations are recommended to address the increased prevalence of anxiety and depression. The consensus also addresses the heightened risk of metabolic, cardiovascular and autoimmune disorders in patients with TS; regular screenings and interventions are advised to manage these conditions effectively. In addition, cardiac abnormalities, including aortic dissections, require regular monitoring and early surgical intervention if certain criteria are met.
Conclusions: The TRAMITI consensus statement provides valuable insights and evidence-based recommendations to guide healthcare practitioners in delivering comprehensive and patient-centered care for patients with TS. By addressing the complex medical and psychosocial aspects of the condition, this consensus aims to enhance TS management and improve the overall well-being and long-term outcomes of these individuals.
(© 2024. The Author(s).)
Databáze: MEDLINE
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