| Autor: |
Antonova IV; Rzhanov Institute of Semiconductor Physics SB RAS, 13 Lavrentiev Av., Novosibirsk 630090, Russia. antonova@isp.nsc.ru.; Department of Semiconductor Devices and Microelectronics, Novosibirsk State Technical University, 20 K. Marx Str., Novosibirsk 630073, Russia., Ivanov AI; Rzhanov Institute of Semiconductor Physics SB RAS, 13 Lavrentiev Av., Novosibirsk 630090, Russia. antonova@isp.nsc.ru., Shavelkina MB; Joint Institute for High Temperatures RAS, Izhorskaya Str. 13 Bd.2, Moscow 125412, Russia., Poteryayev DA; Rzhanov Institute of Semiconductor Physics SB RAS, 13 Lavrentiev Av., Novosibirsk 630090, Russia. antonova@isp.nsc.ru.; Department of Semiconductor Devices and Microelectronics, Novosibirsk State Technical University, 20 K. Marx Str., Novosibirsk 630073, Russia., Buzmakova AA; Department of Semiconductor Devices and Microelectronics, Novosibirsk State Technical University, 20 K. Marx Str., Novosibirsk 630073, Russia., Soots RA; Rzhanov Institute of Semiconductor Physics SB RAS, 13 Lavrentiev Av., Novosibirsk 630090, Russia. antonova@isp.nsc.ru. |
| Abstrakt: |
A unique nanomaterial has been developed for sweat analysis, including glucose level monitoring. Simple resusable low-cost sensors from composite materials based on graphene, hexagonal boron nitride, and conductive PEDOT:PSS (poly(3,4-ethylenedioxythiophene)polystyrene sulfonate) polymer have been developed and fabricated via 2D printing on flexible substrates. The sensors were tested as biosensors using different water-based solutions. A strong increase in the current response (several orders of magnitude) was observed for aqua vapors or glucose solution vapors. This property is associated with the sorption capacity of graphene synthesized in a volume of plasma jets and thus having many active centers on the surface. The structure and properties of graphene synthesized in a plasma are different from those of graphene created by other methods. As a result, the current response for a wearable sensor is 3-5 orders of magnitude higher for the reference blood glucose concentration range of 4-14 mM. It has been found that the most promising sensor with the highest response was fabricated based on the graphene:PEDOT:PSS composite. The graphene:h-BN:PEDOT:PSS (h-BN is hexagonal boron nitride) sensors demonstrated a longer response and the highest response after the functionalization of the sensors with a glucose oxidase enzyme. The reusable wearable graphene:PEDOT:PSS glucose sensors on a paper substrate demonstrated a current response of 10 -10 to 10 -5 A for an operating voltage of 0.5 V and glucose range of 4-10 mM. |
