Evaluation of the effect of Er,Cr:YSGG laser application on peri-implant crevicular fluid receptor activator of nuclear factor-kappa B ligand and osteoprotegerin levels in the non-surgical treatment of peri-implantitis: A randomized clinical trial.

Autor: Alpaslan NZ; Faculty of Dentistry, Department of Periodontology, Van Yuzuncu Yil University, Van, Turkey., Altindal D; Faculty of Dentistry, Department of Periodontology, Van Yuzuncu Yil University, Van, Turkey., Akbal D; Ave Dent Private Clinic, Istanbul, Turkey., Talmac AC; Faculty of Dentistry, Department of Periodontology, Van Yuzuncu Yil University, Van, Turkey., Keskin Tunc S; Hamidiye Faculty of Dental Medicine, Department of Oral and Maxillofacial Surgery, University of Health Sciences, Istanbul, Turkey., Ertugrul AS; Faculty of Dentistry, Department of Periodontology, Izmir Katip Celebi University, Izmir, Turkey.
Jazyk: angličtina
Zdroj: Journal of periodontology [J Periodontol] 2024 Oct; Vol. 95 (10), pp. 917-928. Date of Electronic Publication: 2024 Feb 20.
DOI: 10.1002/JPER.23-0540
Abstrakt: Background: This study aimed to investigate the effect of erbium, chromium doped:yttrium,scandium,gallium,garnet (Er,Cr:YSGG) laser application combined with non-surgical mechanical debridement (MD) on clinical parameters and peri-implant crevicular fluid receptor activator of nuclear factor-kappa B ligand (RANKL) and osteoprotegerin (OPG) levels in the treatment of peri-implantitis.
Methods: A total of 49 patients who underwent non-surgical treatment of peri-implantitis were randomly divided into two groups. The control group (n = 26) received MD alone, while the laser group (n = 23) received MD+Er,Cr:YSGG. The clinical parameters (bleeding on probing [BoP], gingival index [GI], plaque index [PI], probing depth [PD]), marginal bone loss (MBL), and biochemical parameters (RANKL and OPG) were measured at baseline (T0) and 6 months after treatment (T1).
Results: There was a statistically significant decrease in all the clinical parameters in both groups at T1 compared to T0 (p < 0.05). The BoP, PD, MBL, and RANKL reductions were significantly higher in the laser group than in the control group (p = 0.046, p = 0.014, p = 0.047, p = 0.045, respectively). The OPG levels significantly increased at T1 in the laser group (p = 0.01). The OPG/RANKL ratio increased significantly in both groups at T1, which favored the laser group (p = 0.034).
Conclusions: Although both treatment methods were influential in treating peri-implantitis, the laser group (MD+Er,Cr:YSGG) yielded more favorable results by reducing clinical inflammation and improving biochemical parameters. Based on these findings, Er,Cr:YSGG laser may be a beneficial adjunctive treatment in this patient group.
(© 2024 The Author(s). Journal of Periodontology published by Wiley Periodicals LLC on behalf of American Academy of Periodontology.)
Databáze: MEDLINE
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