Neurosarcoidosis and Transverse Myelitis: Life-Threatening Manifestations of Sarcoidosis.
| Autor: | Patel M; Internal Medicine, David Tvildiani Medical University, Tbilisi, GEO., Shiwlani S; Pathology, Mount Sinai Hospital, New York, USA., Kachhadia MP; Internal Medicine, Pandit Dindayal Upadhyay (PDU) College, Civil Hospital Campus, Rajkot, IND., Abdalla M; Internal Medicine, Dallah Hospital, Riyadh, SAU., Samreen I; Internal Medicine, Augusta University, Augusta, USA., Mohamed AS; Neurology, Augusta University, Augusta, USA., Nasir H; Internal Medicine, Mayo Hospital, Lahore, PAK. |
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| Jazyk: | angličtina |
| Zdroj: | Cureus [Cureus] 2024 Jan 20; Vol. 16 (1), pp. e52629. Date of Electronic Publication: 2024 Jan 20 (Print Publication: 2024). |
| DOI: | 10.7759/cureus.52629 |
| Abstrakt: | Sarcoidosis, a systemic granulomatous disorder, typically involves the lungs, skin, and lymph nodes. Neurological manifestations are diverse and may include longitudinally extensive transverse myelitis (LETM), an uncommon inflammatory disorder of the spinal cord. We present a case of a 62-year-old female with LETM as the initial manifestation of sarcoidosis. The patient exhibited progressive bilateral lower extremity weakness, urinary retention, and sensory disturbances. Diagnostic workup revealed characteristic findings on spinal magnetic resonance imaging (MRI), cerebrospinal fluid analysis, and thoracic biopsy. Treatment with high-dose corticosteroids and subsequent immunomodulatory therapy resulted in significant improvement. Our case highlights the importance of including sarcoidosis in the differentials of LETM, particularly in patients with no respiratory manifestations. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2024, Patel et al.) |
| Databáze: | MEDLINE |
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