Early postnatal nutrition and renal consequences in preterm infants.

Autor: Iacobelli S; Réanimation Néonatale et Pédiatrique, CHU La Réunion, Saint-Pierre, France. silvia.iacobelli@chu-reunion.fr.; Centre d'Études Périnatales de l'Océan Indien (UR7388), Université de La Réunion, de La Réunion, France. silvia.iacobelli@chu-reunion.fr., Lapillonne A; Service de Médecine néonatale, CHU La Conception, APHM, Marseille, France.; Aix-Marseille Université, C2VN, INRAe, INSERM, Marseille, France., Boubred F; Department of Neonatology, APHP, Necker-Enfants Malades University Hospital, EHU 7328 Paris Cite University Paris, Paris, France.; CNRC Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.
Jazyk: angličtina
Zdroj: Pediatric research [Pediatr Res] 2024 Feb 19. Date of Electronic Publication: 2024 Feb 19.
DOI: 10.1038/s41390-024-03080-z
Abstrakt: Perinatal nutritional factors may lead to decreased nephron endowment, decreased kidney function, and long-term development of chronic kidney disease and non-communicable diseases. At the same time, optimal postnatal nutrition and catch-up growth are associated with better neurodevelopmental outcomes in preterm infants. Therefore, nutritional management of preterm infants is a major challenge for neonatologists. In this context, the Section of Nutrition, Gastroenterology and Metabolism reviewed the current knowledge on nutritional issues related to kidney function. This narrative review discusses the clinical impact of early postnatal nutrition on long-term kidney function. In preterm infants, data are largely lacking to determine the extent to which early nutrition contributes to nephrogenesis and nephron endowment. However, some nutritional principles may help clinicians better protect the developing kidney in preterm infants. IMPACT: Clinical data show that preterm infants are an emerging population at high risk for chronic kidney disease. Both undernutrition and overnutrition can alter long-term kidney function. In preterm infants, data are largely lacking to determine the extent to which early postnatal nutrition contributes to nephrogenesis, nephron endowment and increased risk for chronic kidney disease. Some nutritional principles may help clinicians better protect the developing kidney in preterm infants: avoiding extrauterine growth restriction; providing adequate protein and caloric intakes; limiting exposure to high and prolonged hyperglycaemia; avoiding micronutrient deficiencies and maintaining acid-base and electrolyte balance.
(© 2024. The Author(s), under exclusive licence to the International Pediatric Research Foundation, Inc.)
Databáze: MEDLINE
Externí odkaz: