Left ventricular recovery in an African cohort of patients with peripartum cardiomyopathy.

Autor: Dangwé Temoua N; Department of Cardiology, National Referral Teaching Hospital of N'Djamena, N'Djamena, Chad.; Faculty of Human Health Sciences, University of N´Djamena, N´Djamena, Chad., Bamouni J; Superior School of Health Sciences, University of Ouahigouya, Ouahigouya, Burkina Faso., Mandi DG; Department of General Medicine, Cardiology Unit, Regional Hospital Center of Tenkodogo, Tenkodogo, Burkina Faso., Kaboré E; Department of General Medicine, Cardiology Unit, Regional Hospital Center of Tenkodogo, Tenkodogo, Burkina Faso., Allawaye L; Department of Cardiology, National Referral Teaching Hospital of N'Djamena, N'Djamena, Chad.; Faculty of Human Health Sciences, University of N´Djamena, N´Djamena, Chad., Langtar MH; Department of Cardiology, National Referral Teaching Hospital of N'Djamena, N'Djamena, Chad., Adjougoulta A; Department of Cardiology, National Referral Teaching Hospital of N'Djamena, N'Djamena, Chad., Douné N; Department of Cardiology, National Referral Teaching Hospital of N'Djamena, N'Djamena, Chad., Adam A; Department of Cardiology, National Referral Teaching Hospital of N'Djamena, N'Djamena, Chad., Zakaria A; Department of Cardiology, National Referral Teaching Hospital of N'Djamena, N'Djamena, Chad., Rélwendé Aristide Y; Training and Research Unit of Health Sciences, University Professor Joseph Ki-Zerbo, Ouagadougou, Burkina Faso., Yibar K; Training and Research Unit of Health Sciences, University Professor Joseph Ki-Zerbo, Ouagadougou, Burkina Faso., Kologo KJ; Training and Research Unit of Health Sciences, University Professor Joseph Ki-Zerbo, Ouagadougou, Burkina Faso., Millogo GRC; Training and Research Unit of Health Sciences, University Professor Joseph Ki-Zerbo, Ouagadougou, Burkina Faso., Yaméogo NV; Training and Research Unit of Health Sciences, University Professor Joseph Ki-Zerbo, Ouagadougou, Burkina Faso., Zabsonré P; Training and Research Unit of Health Sciences, University Professor Joseph Ki-Zerbo, Ouagadougou, Burkina Faso.
Jazyk: angličtina
Zdroj: The Pan African medical journal [Pan Afr Med J] 2024 Jan 05; Vol. 47, pp. 6. Date of Electronic Publication: 2024 Jan 05 (Print Publication: 2024).
DOI: 10.11604/pamj.2024.47.6.42083
Abstrakt: Peripartum cardiomyopathy (PPCM) is a rare and potentially life-threatening disease associated with pregnancy. There are limited data regarding the outcome of PPCM and its predictive factors in sub-Saharan African patients. We prospectively conducted a double-center (cardiology unit of the department of medicine, Regional Hospital Center of Tenkodogo, Burkina Faso and the department of cardiology of the National Referral Teaching Hospital of N´Djamena, Chad) cohort study in patients with PPCM. Patients were consecutively enrolled from January 2015 to December 2017. Outcomes of interest were left ventricular recovery and poor outcome at one year. Ninety-four patients enrolled with a median age of 28 years. At one-year follow-up, 40.5% of them recovered their left ventricular function. Cox multiple regression analysis revealed that higher left ventricle ejection fraction (LVEF), lower natremia and use of betablockers were baseline variables predicting this end-point. Of the entire study population, 26.60% exhibited the composite end-point of death (n=15) or remaining in New York Heart Association (NYHA) class III-IV or LVEF < 35%. Predictors of poor outcome were lower LVEF at baseline, hyponatremia and use of digoxin. The current cohort study demonstrated that PPCM in sub-Saharan Africa is associated with limited myocardial recovery and significant rate of poor outcome at one year. Therefore, additional studies are needed to better address the disease.
Competing Interests: The authors declare no competing interests.
(Copyright: Dangwé Temoua Naïbé et al.)
Databáze: MEDLINE
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