Acute Serum Calcium Level Changes Following Non-Massive Blood and Blood Product Transfusion in Emergency Department; a Cross-sectional Study.

Autor:	Koyuncuoglu HE; Department of Emergency Medicine, Mugla Education and Research Hospital, Mugla, Turkey., Yuksek B; Department of Emergency Medicine, Birecik State Hospital, Sanliurfa, Turkey., Karamercan S; Department of Pediatric Health and Disease, Unit of Pediatric Hematology-Oncology, Faculty of Medicine, Gazi University, Ankara, Turkey., Karamercan MA; Department of Emergency Medicine, Faculty of Medicine, Gazi University, Ankara, Turkey.
Jazyk:	angličtina
Zdroj:	Archives of academic emergency medicine [Arch Acad Emerg Med] 2023 Dec 24; Vol. 12 (1), pp. e19. Date of Electronic Publication: 2023 Dec 24 (Print Publication: 2024).
DOI:	10.22037/aaem.v12i1.2225
Abstrakt:	Introduction: The specific impact on calcium dynamics after non-massive blood transfusions remains relatively unexplored. This study aimed to compare pre- and post-transfusion calcium levels in patients receiving blood and blood product in the emergency department. Methods: This is a single-center, prospective, cross-sectional study conducted at the Emergency Department of Gazi University Health Research and Application Center Hospital in Ankara, Turkey, from January 1, 2020, to August 31, 2020. The study included adult patients who underwent blood and blood product transfusions, and serum calcium levels were measured and compared from samples taken before and after transfusion. Results: A total of 292 participants were enrolled in the study, with 242 participants included in the final analysis. The mean total calcium level was 8.41 ± 0.76 mg/dL before transfusion and 8.34 ± 0.71 mg/dL after transfusion (p=0.012). When examining the corrected calcium values after receiving blood products based on the type of blood products, participants who received apheresis platelets had a post-transfusion corrected calcium value of 8.26 ±0.41 mg/dL, with a pre-transfusion value of 9.09 ±0.49 mg/dL (p<0.01). The post-transfusion ionized calcium value for participants receiving apheresis was 1.04 ±0.08 mg/dL, compared to 1.15 ±0.09 mg/dL for those who did not receive apheresis (p=0.049). There was a significant relationship between receiving fresh frozen plasma and post-transfusion ionized calcium values (p=0.024). Conclusion: This study demonstrated that transfusion-associated hypocalcemia can occur even at mild levels in patients receiving blood and blood product transfusions in the emergency department. However, it is suggested that the clinical effects of hypocalcemia, even when occurring based on the type and quantity of blood products, are minimal and negligible. Competing Interests: The authors declare that they have no competing interests.
Databáze:	MEDLINE
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