In vitro gastrointestinal digestion methods of carbohydrate-rich foods.

Autor: Dávila León R; Escuela Nacional de Ciencias Biológicas Instituto Politécnico Nacional Ciudad de México Mexico., González-Vázquez M; Escuela Nacional de Ciencias Biológicas Instituto Politécnico Nacional Ciudad de México Mexico., Lima-Villegas KE; Escuela Nacional de Ciencias Biológicas Instituto Politécnico Nacional Ciudad de México Mexico., Mora-Escobedo R; Escuela Nacional de Ciencias Biológicas Instituto Politécnico Nacional Ciudad de México Mexico., Calderón-Domínguez G; Escuela Nacional de Ciencias Biológicas Instituto Politécnico Nacional Ciudad de México Mexico.
Jazyk: angličtina
Zdroj: Food science & nutrition [Food Sci Nutr] 2023 Nov 21; Vol. 12 (2), pp. 722-733. Date of Electronic Publication: 2023 Nov 21 (Print Publication: 2024).
DOI: 10.1002/fsn3.3841
Abstrakt: The trend toward healthier food products has led to an increase in the research of in vitro gastrointestinal digestion methods. Among the most used models, static models are the simplest. Most static models have three stages: oral, gastric, and intestinal, simulating the enzymatic, electrolyte, pH, temperature, and bile salt conditions. The studies that have taken the most notice are those related to antioxidant activity, followed by those dealing with proteins and carbohydrates using most of them static in vitro digestion models. The number of these studies has increased over the years, passing from 45 to 415 in a 10-year period (2012-2023) and showing an interest in knowing the impact of food on human health. Nevertheless, published papers report different methodologies and analytical approaches. This review discusses the similarities and differences between the published static in vitro gastrointestinal digestion methods, with a focus on carbohydrates, finding that the most used protocol is Infogest, but with differences, mainly in the type of enzymes and their activity. Regarding in vitro gastrointestinal digestion of carbohydrates, many of the published studies are related to food and biomacromolecules, being the oral phase the most omitted, while the intestinal phase in the most diverse. Other methodologies to study the intestinal phase have been recommended, but the number of in vitro digestion studies using these methodologies (RSIE and BBMV) is still scarce but could represent a good alternative to analyze carbohydrates foods when combining with Infogest. More studies are required in this area.
Competing Interests: The authors confirm that they have no conflict of interest to declare for this publication.
(© 2023 The Authors. Food Science & Nutrition published by Wiley Periodicals LLC.)
Databáze: MEDLINE
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje