Retrospective assessment of ophthalmic disease development in domestic dogs and cats when hospitalised with tick paralysis caused by Ixodes holocyclus.

Autor: Reynolds BD; Eye Clinic for Animals, Sydney, New South Wales, 2064, Australia., Perry E; Northside Emergency Veterinary Service, Sydney, New South Wales, 2084, Australia., Nagel HG; Terrey Hills Animal Hospital, Sydney, New South Wales, 2084, Australia., Whittaker CJ; Eye Clinic for Animals, Sydney, New South Wales, 2064, Australia., Caruso KA; Eye Clinic for Animals, Sydney, New South Wales, 2064, Australia., Annear MJ; Eye Clinic for Animals, Sydney, New South Wales, 2064, Australia., Irving WM; Eye Clinic for Animals, Sydney, New South Wales, 2064, Australia., McCarthy PM; Eye Clinic for Animals, Sydney, New South Wales, 2064, Australia., Dion A; Northside Emergency Veterinary Service, Sydney, New South Wales, 2084, Australia., Yi JS; Northside Emergency Veterinary Service, Sydney, New South Wales, 2084, Australia., Hall E; University of Sydney, Sydney, New South Wales, 2006, Australia., Smith JS; Eye Clinic for Animals, Sydney, New South Wales, 2064, Australia.
Jazyk: angličtina
Zdroj: Australian veterinary journal [Aust Vet J] 2024 Jun; Vol. 102 (6), pp. 296-305. Date of Electronic Publication: 2024 Feb 18.
DOI: 10.1111/avj.13325
Abstrakt: Objective: To investigate the incidence and predisposing factors leading to the development of corneal ulcers and the loss of a palpebral reflex in hospitalised canine and feline patients with tick paralysis (TP).
Animals Studied: A total of 102 dogs and 100 cats retrospectively were assessed from previously hospitalised patients.
Methods: A retrospective cohort study was performed on 102 different canine and 100 different feline patients who were hospitalised for TP from October 2020-January 2022. Patient data were collected, and logistic regression was conducted to determine factors affecting the palpebral reflex and the development of corneal ulcers.
Results: Corneal ulcers occurred in 23/102 (22.5%) dogs during hospitalisation and were strongly associated with an incomplete palpebral reflex ipsilaterally during hospitalisation (P < 0.001), hospitalisation ≥3 days (P = 0.004), mechanical ventilation ≥3 days (P = 0.015) or a tick location cranial to C1 (P = 0.003). An incomplete palpebral reflex during hospitalisation was observed in 29/102 (28.4%) dogs and was significantly associated with decreasing patient weight (P = 0.018), increasing days hospitalised (P = 0.001), having a tick found cranial to C1 (P = 0.004), highest recorded GP grade (P = 0.01), highest recorded RP grade (P = 0.005), use of amoxycillin-clavulanic acid during hospitalisation (P = 0.002) and use of piperacillin/tazobactam during hospitalisation (P = 0.003). There was a significant association between the loss of a complete palpebral reflex and mortality during hospitalisation in dogs (OR = 4.5, P = 0.029). Corneal ulcers occurred in 10/100 (10.0%) cats during hospitalisation, and was significantly more likely to occur to an eye if an incomplete palpebral reflex was observed ipsilaterally during hospitalisation (OR = 20.1, P < 0.0001) and with increasing patient age (P = 0.019). The absence of a complete palpebral reflex during hospitalisation was observed in 18/10 (18.0%) cats and was significantly associated with increasing days hospitalised (P = 0.034). There was no significant association between the loss of a complete palpebral reflex and mortality during hospitalisation in cats.
Conclusions: The frequency of corneal ulcers and loss of palpebral reflexes were significant in dogs and cats hospitalised by TP, with many factors contributing to the risk of these developing.
(© 2024 Australian Veterinary Association.)
Databáze: MEDLINE
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