Hope vs. Hype I: Spreading alpha-synuclein explains cognitive deficits in Parkinson disease.

Autor: Mills KA; Johns Hopkins Department of Neurology, Baltimore, MD600 N. Wolfe Street, Meyer 6-181D, 21287, United States. Electronic address: kmills16@jhmi.edu., Phillips O; Geisel School of Medicine at Dartmouth, Hanover, NH, 18 Old Etna Road, 03756, United States. Electronic address: Oliver.Phillips@dartmouth.edu., Mahajan A; The University of Cincinnati James J. and Joan A. Gardner Family Center for Parkinson's Disease and Movement Disorders, OH, 260 Stetson St., Suite 2300, Cincinnati, 45219, United States. Electronic address: mahajaau@ucmail.uc.edu.
Jazyk: angličtina
Zdroj: Parkinsonism & related disorders [Parkinsonism Relat Disord] 2024 Sep; Vol. 126, pp. 106042. Date of Electronic Publication: 2024 Feb 11.
DOI: 10.1016/j.parkreldis.2024.106042
Abstrakt: The Parkinson Study Group (PSG) gathered North American experts in Parkinson disease during the 9 th  Annual Symposium on "Shaping the Management of Parkinson Disease: Debating Current Controversies". Debaters were tasked with agree or disagree positions to a particular prompt. This is the first in three-part series of "Hype vs. Hope" debates involving current trends and advances in Parkinson disease. With the prompt of "Spreading alpha-synuclein explains cognitive deficits in Parkinson disease," Dr. Kelly Mills, MD, MHS was tasked with the "agree" stance and Dr. Abhimanyu Mahajan, MD, MHS was tasked with the "disagree" stance. The following point-of-view article is an adaptation of this debate.
Competing Interests: Declaration of Competing interest Dr. Mills: Dr. Mills has no conflicts of interest to disclose. Dr. Mahajan: Dr. Mahajan has no conflicts of interest to disclose. Dr. Phillips: Dr. Phillips has no conflicts of interest to disclose.
(Copyright © 2024 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE