Peptidyl-tRNA hydrolase as a key player in the liberation of truncated nascent chains from the ribosomal subunit.
| Autor: | Rodnina MV; Max Planck Institute for Multidisciplinary Sciences, Goettingen, Germany. Electronic address: rodnina@mpibpc.mpg.de. |
|---|---|
| Jazyk: | angličtina |
| Zdroj: | Molecular cell [Mol Cell] 2024 Feb 15; Vol. 84 (4), pp. 614-615. |
| DOI: | 10.1016/j.molcel.2024.01.017 |
| Abstrakt: | Svetlov et al. identify the enzyme peptidyl-tRNA hydrolase as a ribosome-associated quality-control factor that promotes hydrolysis of the dislodged peptidyl-tRNA, which helps to recycle ribosomal subunits blocked by truncated nascent chains in bacteria. Competing Interests: Declaration of interests The author declares no competing interests. (Copyright © 2024 Elsevier Inc. All rights reserved.) |
| Databáze: | MEDLINE |
| Externí odkaz: |
|