Rapid testing for respiratory syncytial virus in a resource-limited paediatric intensive care setting.
| Autor: | Newman H; National Health Laboratory Service, Virology, Port Elizabeth, South Africa.; Department of Pathology, Division of Medical Virology, Stellenbosch University, Cape Town, South Africa.; Faculty of Health Sciences, Nelson Mandela University, Port Elizabeth, South Africa., Tshabalala D; Department of Paediatrics, Nelson Mandela Academic Hospital, Mthatha, South Africa.; Department of Paediatrics, Walter Sisulu University, Mthatha, South Africa., Mabunda S; Department of Public Health, Walter Sisulu University, Mthatha, South Africa.; Mpumalanga Department of Health, Nelspruit, South Africa., Nkosi N; Department of Pathology, Division of Medical Virology, Stellenbosch University, Cape Town, South Africa.; National Health Laboratory Service, Tygerberg Academic Hospital, Cape Town, South Africa., Carelson C; National Health Laboratory Service, Virology, Port Elizabeth, South Africa. |
|---|---|
| Jazyk: | angličtina |
| Zdroj: | African journal of laboratory medicine [Afr J Lab Med] 2020 Dec 08; Vol. 9 (1), pp. 1084. Date of Electronic Publication: 2020 Dec 08 (Print Publication: 2020). |
| DOI: | 10.4102/ajlm.v9i1.1084 |
| Abstrakt: | We analysed the performance characteristics of the respiratory syncytial virus lateral flow rapid antigen assay in use when compared to a multiplex polymerase chain reaction for detection of respiratory viruses. The study was conducted at a tertiary paediatric hospital in Port Elizabeth, South Africa, from 01 January 2017 to 31 December 2018. We found the clinical sensitivity (36.8%) of the rapid test to be too low for routine diagnostic use. Knowledge of assay performance characteristics of rapid tests are important for appropriate interpretation of rapid test results. Competing Interests: The authors have declared that no competing interests exist. (© 2020. The Authors.) |
| Databáze: | MEDLINE |
| Externí odkaz: |
|