Burkitt Lymphoma Presenting as Ileocolic Intussusception in an Adult.

Autor:	Borré CI; Yale School of Public Health, Yale University, New Haven, USA., Boyle B; Department of Medicine, Mayo Clinic, Rochester, USA., Lynch K; Department of Medicine, Mayo Clinic, Rochester, USA., Kanaparthi A; Department of Medicine, Mayo Clinic, Rochester, USA., Csizmar CM; Department of Medicine, Mayo Clinic, Rochester, USA., Larson DP; Division of Hematopathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, USA., Braithwaite MD; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, USA., Johnson IM; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, USA., Witzig TE; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, USA., Suarez DA; Division of Community Internal Medicine, Department of Medicine, Mayo Clinic, Rochester, USA.
Jazyk:	angličtina
Zdroj:	Open journal of blood diseases [Open J Blood Dis] 2023 Dec; Vol. 13 (4), pp. 121-132. Date of Electronic Publication: 2023 Dec 08.
DOI:	10.4236/ojbd.2023.134014
Abstrakt:	Adult intussusception is rare, highly associated with a malignant lead point, and often requires emergent surgical management. We report the case of a 44-year-old male who presented with generalized abdominal pain and was found to have early ileocolic intussusception secondary to a large ileocecal mass. Biopsies of the mass and an enlarged cardiophrenic lymph node, as well as pleural fluid cytology were all consistent with Burkitt lymphoma (BL). Curiously, the patient's abdominal exam was reassuring, and the intussusception and malignant bowel obstruction resolved over 36 hours with conservative management alone. With a Burkitt lymphoma international prognostic index (BL-IPI) score of 2, the patient proceeded to treatment with combination chemoimmunotherapy and attained a complete response after four cycles. There was no bowel perforation or recurrent intussusception throughout treatment. Thus, this report marks the first reported case of adult BL-associated intussusception to resolve with non-invasive management and establishes a precedent for conservative management in select patients. Competing Interests: Conflicts of Interest The authors declare no conflicts of interest regarding the publication of this paper.
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu