Evaluation of risk factors for sleep-disordered breathing in dogs.

Autor: Niinikoski I; Department of Equine and Small Animal Medicine, University of Helsinki, Helsinki, Finland., Himanen SL; Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.; Department of Clinical Neurophysiology, Tampere University Hospital, Wellbeing Services County of Pirkanmaa, Tampere, Finland., Tenhunen M; Department of Clinical Neurophysiology, Tampere University Hospital, Wellbeing Services County of Pirkanmaa, Tampere, Finland.; Department of Medical Physics, Tampere University Hospital, Wellbeing Services County of Pirkanmaa, Tampere, Finland., Aromaa M; Department of Equine and Small Animal Medicine, University of Helsinki, Helsinki, Finland., Lilja-Maula L; Department of Equine and Small Animal Medicine, University of Helsinki, Helsinki, Finland., Rajamäki MM; Department of Equine and Small Animal Medicine, University of Helsinki, Helsinki, Finland.
Jazyk: angličtina
Zdroj: Journal of veterinary internal medicine [J Vet Intern Med] 2024 Mar-Apr; Vol. 38 (2), pp. 1135-1145. Date of Electronic Publication: 2024 Feb 15.
DOI: 10.1111/jvim.17019
Abstrakt: Background: Brachycephalic dogs display sleep-disordered breathing (SDB). The risk factors for SDB remain unknown.
Objectives: To identify risk factors for SDB. We hypothesized that brachycephaly, increasing severity of brachycephalic obstructive airway syndrome (BOAS), excess weight, and aging predispose to SDB.
Animals: Sixty-three privately owned pet dogs were prospectively recruited: 28 brachycephalic and 35 normocephalic (mesaticephalic or dolicocephalic) dogs.
Methods: Prospective observational cross-sectional study with convenience sampling. Recording with the neckband was done over 1 night at each dog's home. The primary outcome measure was the obstructive respiratory event index (OREI). Body condition score (BCS) was assessed, and BOAS severity was graded for brachycephalic dogs.
Results: Brachycephaly was a significant risk factor for high OREI value (ratio of the geometric means 5.6, 95% confidence interval [CI] 3.2-9.9; P < .001) but aging was not (1.1, 95% CI 1.0-1.2; P = .2). Excess weight, defined as a BCS of over 5/9, (3.5, 95% CI 1.8-6.7; P < .001) was a significant risk factor. In brachycephalic dogs, BOAS-positive class (moderate or severe BOAS signs) was a significant risk factor (2.5, 95% CI 1.1-5.6; P = .03).
Conclusions and Clinical Importance: Brachycephaly decreases welfare in a multitude of ways, including disrupting sleep. Brachycephaly, increasing severity of BOAS and excess weight are risk factors for obstructive SDB.
(© 2024 The Authors. Journal of Veterinary Internal Medicine published by Wiley Periodicals LLC on behalf of American College of Veterinary Internal Medicine.)
Databáze: MEDLINE
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