Takotsubo syndrome : A cause of reversible microvascular coronary dysfunction.

Autor: Zeitouni M; Sorbonne Université, ACTION Study Group, INSERM UMRS 1166, Institut de Cardiologie, Hôpital Pitié-Salpêtrière (AP-HP), Paris, 75013, France.. Electronic address: michel.zeitouni@aphp.fr., Procopi N; Sorbonne Université, ACTION Study Group, INSERM UMRS 1166, Institut de Cardiologie, Hôpital Pitié-Salpêtrière (AP-HP), Paris, 75013, France., Redheuil A; Sorbonne Université, ICT Unité d'imagerie cardiovasculaire et thoracique, Hôpital La Pitié Salpêtrière (AP-HP), Laboratoire d'Imagerie Biomédicale, INSERM UMRS 1146, CNRS, Institute of Cardiometabolism and Nutrition, Paris, France., Collet JP; Sorbonne Université, ACTION Study Group, INSERM UMRS 1166, Institut de Cardiologie, Hôpital Pitié-Salpêtrière (AP-HP), Paris, 75013, France.
Jazyk: francouzština
Zdroj: Annales de cardiologie et d'angeiologie [Ann Cardiol Angeiol (Paris)] 2024 Apr; Vol. 73 (2), pp. 101734. Date of Electronic Publication: 2024 Feb 14.
DOI: 10.1016/j.ancard.2024.101734
Abstrakt: Since the first description of takotsubo syndrome 30 years ago, only a little is known on the underlying physiopathology leading to peculiar left ventricular function alteration and myocardial damage related to acute emotional or physical stress. In the present case, we used continuous invasive thermodilution to evaluate coronary microvascular function at the acute phase of takotsubo and after recovery. The acute phase of takotsubo was characterized by a reduced coronary output and altered reserved flow with persistently high resistance during hyperaemia. At 6 weeks, we described a complete recovery of microvascular function, concomitant to LVEF recovery.
Competing Interests: Disclosure of interest Dr M. Zeitouni has research grants or honorariums from Bayer, BMS Pfizer, la Fédération Française de Cardiologie, Servier, Amgen, AstraZeneca, NovoNordisk. Pr Collet has research grants or honorariums from AstraZeneca, Boston Scientific, Bristol-Myers Squibb, COR2ED, Lead-Up, Medtronic, WebMD. The authors have nothing to disclose.
(Copyright © 2024 Elsevier Masson SAS. All rights reserved.)
Databáze: MEDLINE
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