Serum albumin adjusted calcium and fluoride among type 2 diabetes mellitus patients.

Autor: Dubey SD; Sri Devaraj Urs Medical College constituent of Sri Devaraj Urs Academy of Higher Education and Research, Kolar, India., Nagaraj SK; Department of Biochemistry, Sri Devaraj Urs Medical College constituent of Sri Devaraj Urs Academy of Higher Education and Research, Kolar, India., Rangareddy H; Department of Biochemistry, Haveri Institute of Medical Sciences, Haveri, India.
Jazyk: angličtina
Zdroj: Bioinformation [Bioinformation] 2024 Jan 31; Vol. 20 (1), pp. 65-69. Date of Electronic Publication: 2024 Jan 31 (Print Publication: 2024).
DOI: 10.6026/973206300200065
Abstrakt: The regulation of glucose-dependent insulin secretion in pancreatic β-cells relies on calcium concentration, making it a calcium-dependent process. Disruptions in calcium homeostasis may contribute to insulin dysfunction and disturbances in glucose homeostasis, potentially playing a role in the development of type 2 diabetes mellitus (T2DM). In T2DM patients, there may be changes in fluoride metabolism due to impaired renal function. Measurement of serum albumin-adjusted calcium and is crucial since changes in albumin levels can impact the accurate estimation of true calcium.
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Databáze: MEDLINE