[Diagnosis of neurocysticercosis in patients with epilepsy living in the south-western Dominican Republic].

Autor:	Rivera D; Universidad Nacional Pedro Henríquez Ureña, Santo Domingo, República Dominicana.; Centros de Diagnóstico y Medicina Avanzada y de Conferencias Médicas y Telemedicina, Santo Domingo, República Dominicana., Santos D; Universidad Autónoma de Santo Domingo, Santo Domingo, República Dominicana.; Hospital Dr. Luis Eduardo Aybar, Santo Domingo, República Dominicana., Carmant L; Ministerio de Salud y Asuntos Sociales, Québec, Canadá., García HH; Universidad Peruana Cayetano Heredia, Lima, Perú., Pimentel R; Centro de Educación Médica de Amistad Dominico-Japonesa, Santo Domingo, República Dominicana., Wiebe S; University of Calgary, Calgary, Canadá., Aponte V; Sistema Nacional de Salud, Madrid, España., González L; Hospital Pedro Emilio de Marchena, Monseñor Nouel, República Dominicana., Castillo JC; Two Oceans in Health, Santo Domingo, República Dominicana., Matos B; Centro Médico Anacaona, San Juan, República Dominicana., Paliza JM; Neurorradiología Diagnóstica SA, Santo Domingo, República Dominicana., Fermín R; Centros de Diagnóstico y Medicina Avanzada y de Conferencias Médicas y Telemedicina, Santo Domingo, República Dominicana., Stoeter P; Centros de Diagnóstico y Medicina Avanzada y de Conferencias Médicas y Telemedicina, Santo Domingo, República Dominicana., Pérez-Then E; Two Oceans in Health, Santo Domingo, República Dominicana.; Universidad Dominicana, Santo Domingo, República Dominicana.
Jazyk:	Spanish; Castilian
Zdroj:	Revista de neurologia [Rev Neurol] 2024 Feb 16; Vol. 78 (4), pp. 109-116.
DOI:	10.33588/rn.7804.2023289
Abstrakt:	Introduction: Neurocysticercosis (NCC), a possible cause of epilepsy with limited epidemiological data in the Dominican Republic, is endemic in four provinces in the country's south-western region. This study aimed to determine the association between NCC and epilepsy among people living in these endemic regions, and to obtain preliminary data on the prevalence of NCC in these provinces. Patients and Methods: A case-control design was used, consisting of 111 patients with epilepsy with unknown causes, and 60 controls without epilepsy or NCC. The diagnosis of NCC was based on computed tomography and magnetic resonance imaging of the skull, as well as Western immunoblotting for serum antibodies using Taenia solium, following the criteria of Del Brutto et al. RESULTS. NCC was found in 27% of the epileptic patients (n = 30/111) and in 5% of the controls (n = 3/60); the probability of the epileptic patients having NCC was seven times higher than the controls (odds ratio = 7.04, 95% confidence interval: 2.04-24.18; p < 0.001). The participants' sociodemographic characteristics, including their age, sex, level of education, occupation, and province of residence presented no statistical significance in terms of their association with NCC. Conclusions: This study suggests that NCC is strongly associated with epilepsy in the south-western region of the Dominican Republic, and highlights the need for public health measures to improve the prevention, diagnosis and treatment of both diseases.
Databáze:	MEDLINE
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