Plasma Levels of Magnesium, Calcium, Calcium to Magnesium Ratio, and Associations with Metabolic Syndrome and Cardiometabolic Risk Factors.

Autor: Moia MN; Postgraduate Program in Nutrition, Center for Health Sciences, Federal University of Rio Grande do Norte, Av. Senador Salgado Filho 3000 - Lagoa Nova, Natal, Rio Grande do Norte, 59078-900, Brazil., Lima SCVC; Department of Nutrition, Center for Health Sciences, Federal University of Rio Grande do Norte, Av. Senador Salgado Filho 3000 - Lagoa Nova, Natal, Rio Grande do Norte, 59078-900, Brazil., da Silva Nunes FL; Postgraduate Program in Nutrition, Center for Health Sciences, Federal University of Rio Grande do Norte, Av. Senador Salgado Filho 3000 - Lagoa Nova, Natal, Rio Grande do Norte, 59078-900, Brazil., Queiroz SIML; Postgraduate Program in Collective Health, Health Sciences Center, Federal University of Rio Grande do Norte, Av. Senador Salgado Filho 3000 - Lagoa Nova, Natal, Rio Grande do Norte, 59078-900, Brazil., Marchioni DML; Department of Nutrition, School of Public Health, University of São Paulo, São Paulo Campus, Av. Dr. Arnaldo, 715 - Cerqueira César, São Paulo, São Paulo, 01246-904, Brazil., Pedrosa LFC; Postgraduate Program in Nutrition, Center for Health Sciences, Federal University of Rio Grande do Norte, Av. Senador Salgado Filho 3000 - Lagoa Nova, Natal, Rio Grande do Norte, 59078-900, Brazil., Barbosa F Jr; Laboratory of Clinical, Toxicological and Bromatological Analysis, Faculty of Pharmaceutical Sciences, University of São Paulo, Ribeirão Preto Campus, Av. Do Café, s/n - Monte Alegre, Ribeirão Preto, São Paulo, 14040-903, Brazil., de Oliveira Lyra C; Department of Nutrition, Center for Health Sciences, Federal University of Rio Grande do Norte, Av. Senador Salgado Filho 3000 - Lagoa Nova, Natal, Rio Grande do Norte, 59078-900, Brazil., Sena-Evangelista KCM; Department of Nutrition, Center for Health Sciences, Federal University of Rio Grande do Norte, Av. Senador Salgado Filho 3000 - Lagoa Nova, Natal, Rio Grande do Norte, 59078-900, Brazil. karine.sena@ufrn.br.; Department of Nutrition, Federal University of Rio Grande do Norte, Av. Senador Salgado Filho 3000 - Lagoa Nova, Natal, Rio Grande do Norte, 59078-900, Brazil. karine.sena@ufrn.br.
Jazyk: angličtina
Zdroj: Biological trace element research [Biol Trace Elem Res] 2024 Dec; Vol. 202 (12), pp. 5307-5318. Date of Electronic Publication: 2024 Feb 12.
DOI: 10.1007/s12011-024-04088-6
Abstrakt: Magnesium and calcium are elements that have been associated with cardiometabolic risk factors related to metabolic syndrome (MetS). However, there are gaps in the knowledge regarding the impact of the calcium to magnesium (Ca/Mg) ratio in plasma. Thus, we aim to evaluate the associations between magnesium and calcium levels in plasma, and the Ca/Mg ratio in plasma with MetS components and other cardiometabolic risk factors. This cross-sectional study was carried out with 112 adults and older people, distributed into groups with (n = 60) and without MetS (n = 52). We evaluated sociodemographic, anthropometric, and biochemical data. Magnesium and calcium levels in plasma were measured by inductively coupled plasma mass spectrometry technique (ICP-MS). There was a high frequency of MetS, with no significant differences in magnesium and calcium levels and Ca/Mg ratio in plasma observed between groups. There were no associations between magnesium and MetS components or other cardiometabolic risk factors (all p > 0.05). Calcium levels were associated with total cholesterol (β =  - 0.020; p = 0.000) and high-density lipoprotein cholesterol (HDL-c) (β =  - 0.046; p = 0.005). The total cholesterol (β =  - 0.025; p = 0.000) and low-density lipoprotein cholesterol (LDL-c) (β = 0.017; p = 0.020) were preditors of the Ca/Mg ratio. These results indicate important associations of calcium and the Ca/Mg ratio in plasma with cardiometabolic risk factors related to MetS.
(© 2024. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)
Databáze: MEDLINE
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