Increased ventilator utilization, ventilator-associated pneumonia, and mortality in non-COVID patients during the pandemic.

Autor: Okpujie VO; Department of Internal Medicine, University of Benin Teaching Hospital, Benin City, Edo State, Nigeria., Uwumiro FE; Department of Internal Medicine, University of Benin Teaching Hospital, Benin City, Edo State, Nigeria., Bojerenu M; Department of Internal Medicine, St. Barnabas Hospital SBH Health System, Bronx, New York, USA., Alemenzohu H; College of Medicine, University of Ibadan, Ibadan, Oyo State, Nigeria., Obi ES; Department of Internal Medicine, East Tennessee State University, Johnson City, Tennessee, USA., Chigbu NC; Department of Internal Medicine, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana., Ibrahim AA; College of Medicine and Health Sciences, Afe Babalola University, Ado-Ekiti, Ekiti State, Nigeria., Okafor N; All Saints University College of Medicine, Belair Kingstown, St. Vincent & The Grenadines., Aghomon A; College of Medicine, University of Lagos, Lagos,Nigeria., Obidike A; Chukwuemeka Odumegwu Ojukwu University Teaching Hospital, Awka, Anambra State, Nigeria.
Jazyk: angličtina
Zdroj: Proceedings (Baylor University. Medical Center) [Proc (Bayl Univ Med Cent)] 2024 Feb 08; Vol. 37 (2), pp. 230-238. Date of Electronic Publication: 2024 Feb 08 (Print Publication: 2024).
DOI: 10.1080/08998280.2024.2301783
Abstrakt: Background: This study examined ventilator utilization, ventilator-associated pneumonia (VAP) incidence, and mortality among non-COVID patients requiring mechanical ventilation during 2019 and 2020.
Methods: The Nationwide Inpatient Sample database was queried for adult hospitalizations with mechanical ventilation using ICD-10 procedure codes, excluding COVID-19 patients and minors. VAP rates were calculated per 1000 adults ventilated. Outcomes included ventilation rates, VAP incidence, and mortality odds between prepandemic and pandemic-exposed hospitalizations.
Results: Analyzing 1,533,775 hospitalizations, the pandemic-exposed had more male patients (57.6% vs 56.2%, P  < 0.001) and nonelective admissions (95.4% vs 94.1%; P  < 0.001). Non-COVID patients had a 4.5% increase in ventilator utilization in the pandemic compared with the prepandemic period ( P  < 0.001). Pandemic VAP incidence was 17 cases per 1000 adults ventilated, compared to 11 cases in the prepandemic period ( P  < 0.001). Mortality rates increased from 26.9% to 31.4%, with 314 mortalities per 1000 ventilated pandemic patients compared with 269 in the prepandemic period (adjusted odds ratio 1.13; 95% confidence interval 1.12-1.15; P  < 0.001).
Conclusion: Significant ventilator utilization, VAP rates, and mortality increases occurred during the COVID-19 pandemic.
Competing Interests: The authors report no funding or conflict of interest.
(Copyright © 2024 Baylor University Medical Center.)
Databáze: MEDLINE