A Comparative Analysis of Three Antioxidants in Addition to Scaling and Root Planing in Stage Three Grade B Periodontitis.

Autor:	Saha S; Department of Periodontology, Chhattisgarh Dental College and Research Institute, Rajnandgaon, IND., Mahilkar S; Department of Dentistry, Government Medical College, Mahasamund, IND., Abraham DV; Department of Periodontics, Maitri College of Dentistry and Research Center, Durg, IND., S S; Department of Oral Pathology and Microbiology, Dent Inn Dental Clinic, Thiruvananthapuram, IND., Bhat N; Department of Preventive Dental Sciences, Al Baha University, Al Baha, SAU., Srivastava DS; Department of Oral Medicine and Radiology, Teerthanker Mahaveer Dental College, Moradabad, IND.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2024 Jan 08; Vol. 16 (1), pp. e51916. Date of Electronic Publication: 2024 Jan 08 (Print Publication: 2024).
DOI:	10.7759/cureus.51916
Abstrakt:	Introduction: The main feature of periodontitis is the development of periodontal pockets as a secondary consequence, which is mainly caused by an excessive immune response to the dental biofilm. The prime factor in the pathogenesis of periodontitis is an increase in oxidative stress. Numerous clinical studies have demonstrated that antioxidant supplementation can reduce endogenous antioxidant depletion and the oxidative damage that goes along with it. Hence, antioxidant therapy in the treatment of periodontal disease may prove to be a promising tool. Objective: The objective of the study is to compare the efficiency of three different antioxidants as oral supplements. Materials and Methods: Eighty patients with chronic periodontitis were randomly split into four groups. The control group received scaling and root planning (SRP), and the test group received oral supplements for 30 days with SRP. Pocket depth (PD), clinical attachment level (CAL), oral hygiene index-simplified (OHI-S), and sulcus bleeding index (SBI) were evaluated at baseline and 30 days. The analysis of the data was done with ANOVA, Kruskal-Wallis, and post hoc tests. The significance level was set at p<0.05 and p<0.001. Results: All groups resulted in a statistically significant reduction in all parameters from baseline to one month. The treatment groups revealed a statistically significant reduction in PD and CAL (p<0.00) but no reduction in OHI-S and SBI (p>0.05) scores. A highly statistically significant reduction was observed in PD with green coffee bean extract when compared with other groups. Conclusion: Green coffee bean extract oral supplements may prove to be a promising appendage in therapeutic and prophylactic fashion, along with SRP, in the treatment of stage III grade B periodontitis patients. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2024, Saha et al.)
Databáze:	MEDLINE
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