The role of coenzyme Q10 as a preventive and therapeutic agent for the treatment of cancers.

Autor: Ghasempour Dabaghi G; School of Medicine, Isfahan University of Medical Science, Isfahan, Iran., Rabiee Rad M; School of Medicine, Isfahan University of Medical Science, Isfahan, Iran., Mohammad-Zamani M; School of Medicine, Isfahan University of Medical Science, Isfahan, Iran., Karimi Shervedani A; School of Medicine, Isfahan University of Medical Science, Isfahan, Iran., Bahrami-Samani F; School of Medicine, Isfahan University of Medical Science, Isfahan, Iran., Heshmat-Ghahdarijani K; Heart Failure Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Shahid Rahmani Alley, Moshtagh Sevom St., Isfahan, Iran. Electronic address: kiyan_heshmat@yahoo.com.
Jazyk: angličtina
Zdroj: Current problems in cancer [Curr Probl Cancer] 2024 Feb; Vol. 48, pp. 101063. Date of Electronic Publication: 2024 Feb 07.
DOI: 10.1016/j.currproblcancer.2024.101063
Abstrakt: Currently, several options are available for the prevention and treatment of cancers; however, many limitations remain with these approaches. Recently, antioxidants have become important preventive and therapeutic alternatives with few adverse events and minimum cost. Coenzyme Q10 (CoQ10) is a naturally occurring component that performs an anticancer function by reducing oxidative stress. CoQ10 supplementation as an adjuvant therapy offers more progress in the elimination and development of cancers. This review aimed to critically assess and summarize the implication of CoQ10 in cancers, highlighting possible mechanisms, and future directions of research for the standardization of the current regimen for cancer prevention and treatment.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024. Published by Elsevier Inc.)
Databáze: MEDLINE
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