Pulmonary tuberculosis in an adult presenting with severe hyponatremia: A case report and review of literature.

Autor: Paudel S; Patan Academy of Health Sciences Lalitpur Nepal.; Team Erevnites Trivandrum India., Dhanani M; Team Erevnites Trivandrum India.; Southwestern University School of Medicine Cebu City Philippines., Patel KH; Team Erevnites Trivandrum India.; Government Medical College Surat India., Vakkalagadda NP; Team Erevnites Trivandrum India.; Guntur Medical College Guntur Andhra Pradesh India., Sanker V; Team Erevnites Trivandrum India.; Noorul Islam Institute of Medical Sciences Trivandrum Kerala India., Damera AR; Team Erevnites Trivandrum India.; Mediciti Institute of Medical Sciences Ghanpur Telangana India., Gupta U; Team Erevnites Trivandrum India.; Nepalgunj medical college Nepalgunj Banke Nepal., Bhandari P; Patan Academy of Health Sciences Lalitpur Nepal.; Team Erevnites Trivandrum India.
Jazyk: angličtina
Zdroj: Clinical case reports [Clin Case Rep] 2024 Feb 06; Vol. 12 (2), pp. e8469. Date of Electronic Publication: 2024 Feb 06 (Print Publication: 2024).
DOI: 10.1002/ccr3.8469
Abstrakt: Key Clinical Message: Identifying pulmonary pathology while evaluating electrolyte disorders is crucial for optimal patient management. Physicians working in endemic regions of tuberculosis should consider this pathology as a differential for electrolyte imbalances.
Abstract: Hyponatremia, a common electrolyte imbalance, can arise from various underlying etiologies such as diuretics, diarrhea, vomiting, congestive heart failure, and liver and renal disease. We present a case report of a 74-year-old man highlighting the association between pulmonary tuberculosis (TB) and the development of hyponatremia. GeneXpert assay of the patient's sputum sample led to the identification of underlying active pulmonary TB as the cause of hyponatremia. The patient was started on anti-TB therapy, and concurrent fluid restriction and sodium supplementation were initiated to correct the electrolyte imbalance. Over the next 3 days, the patient demonstrated clinical improvement with the resolution of hyponatremia. This case also highlights the importance of considering TB as a potential etiology in patients presenting with hyponatremia, especially in endemic areas. Further research is warranted to explore the mechanistic pathways linking pulmonary TB and hyponatremia, aiding in the development of targeted therapeutic interventions.
Competing Interests: None declared.
(© 2024 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.)
Databáze: MEDLINE
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