Environmental asbestos exposure from nephrite jade mining and lung cancer.

Autor:	Yang HY; Institute of Environmental and Occupational Health Sciences, National Taiwan University College of Public Health, 10055, Taipei, Taiwan; Department of Public Health, National Taiwan University College of Public Health, 10055, Taipei, Taiwan; Department of Environmental and Occupational Medicine, National Taiwan University Hospital, 100225, Taipei, Taiwan; Population Health Research Center, National Taiwan University, Taiwan. Electronic address: hyang@ntu.edu.tw., Furuya S; Japan Occupational Safety and Health Resource Center, 136-0071, Tokyo, Japan., Toyama N; Tokyo Occupational Safety and Health Center, 136-0071, Tokyo, Japan.
Jazyk:	angličtina
Zdroj:	Journal of the Formosan Medical Association = Taiwan yi zhi [J Formos Med Assoc] 2024 Jul; Vol. 123 (7), pp. 796-801. Date of Electronic Publication: 2024 Feb 06.
DOI:	10.1016/j.jfma.2024.01.029
Abstrakt:	Background: Nephrite is an asbestos mineral composed of tremolite and actinolite. Fengtian is a community where nephrite was mined between 1970 and 1980 and asbestos was mined between 1960 and 1985. The lung cancer risk to the surrounding community is unknown. Aims: To analyse the trend of lung cancer caused by environmental contamination from nephrite mining. Methods: We conducted a field survey of nephrite mines and tracked new cases of lung cancer from 1980 to 2019. We calculated the age-standardized incidence rates (ASIRs) and applied join-point regression to examine the lung cancer trend. We assessed the age effect, period effect, and birth cohort effect on lung cancer risk. Results: The nephrite mines were contaminated with chrysotile and tremolite/actinolite asbestos. A total of 278 new cases of lung cancer were reported during the study period. There was an apparent age effect and a slight period effect for lung cancer. After adjustment for the age and period effects, the birth cohort born between 1970 and 1980 during the period of nephrite mass production had the highest relative risk compared with other birth cohorts. The ASIR of lung cancer increased significantly from 1980 to 2010 (the annual percentage change = 6.8 %, 95 % CI: 4.0-9.7 %, P < 0.01) and then decreased 30 years after the cessation of nephrite jade mining. Conclusion: Nephrite mining increases the risk of lung cancer in nearby communities. Competing Interests: Declaration of competing interest All authors declare that they did not have any competing interests or any financial or personal relationships that might bias this work. (Copyright © 2024 Formosan Medical Association. Published by Elsevier B.V. All rights reserved.)
Databáze:	MEDLINE
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