| Autor: |
Djuicy DD, Sadeuh-Mba SA, Bilounga CN, Yonga MG, Tchatchueng-Mbougua JB, Essima GD, Esso L, Nguidjol IME, Metomb SF, Chebo C, Agwe SM, Ankone PA, Ngonla FNN, Mossi HM, Etoundi AGM, Eyangoh SI, Kazanji M, Njouom R |
| Jazyk: |
angličtina |
| Zdroj: |
Emerging infectious diseases [Emerg Infect Dis] 2024 Mar; Vol. 30 (3), pp. 432-443. Date of Electronic Publication: 2024 Feb 07. |
| DOI: |
10.3201/eid3003.230861 |
| Abstrakt: |
During 1979-2022, Cameroon recorded 32 laboratory-confirmed mpox cases among 137 suspected mpox cases identified by the national surveillance network. The highest positivity rate occurred in 2022, indicating potential mpox re-emergence in Cameroon. Both clade I (n = 12) and clade II (n = 18) monkeypox virus (MPXV) were reported, a unique feature of mpox in Cameroon. The overall case-fatality ratio of 2.2% was associated with clade II. We found mpox occurred only in the forested southern part of the country, and MPXV phylogeographic structure revealed a clear geographic separation among concurrent circulating clades. Clade I originated from eastern regions close to neighboring mpox-endemic countries in Central Africa; clade II was prevalent in western regions close to West Africa. Our findings suggest that MPXV re-emerged after a 30-year lapse and might arise from different viral reservoirs unique to ecosystems in eastern and western rainforests of Cameroon. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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