Analytical performance of feline plasma on current Heska and IDEXX point-of-care biochemistry analyzers compared with a commercial laboratory analyzer.
Autor: | Baral RM; University of Sydney/Paddington Cat Hospital, Sydney, Australia., Jaensch SM; Vetnostics, Sydney, Australia., Hayward DA; Vetnostics, Sydney, Australia., Freeman KP; Veterinary Information Network, Davis, California, USA. |
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Jazyk: | angličtina |
Zdroj: | Veterinary clinical pathology [Vet Clin Pathol] 2024 Sep; Vol. 53 (3), pp. 343-357. Date of Electronic Publication: 2024 Feb 06. |
DOI: | 10.1111/vcp.13310 |
Abstrakt: | Background: Point-of-care (POC) biochemistry analyzers are widely used in small animal clinical practice but infrequently independently assessed for performance. Objective: To assess the performance of two current model point-of-care biochemistry analyzers (Heska Element DC and IDEXX Catalyst) compared with a commercial laboratory analyzer (Cobas 8000). Methods: One hundred twenty-one cats from a feline hospital population were sampled with plasma results from a single lithium heparin tube assessed on all three analyzers. Plasma biochemistry results from each POC analyzer were compared with the commercial laboratory analyzer using Bland-Altman difference plots and by determining whether the limits of agreement (LOAs) (95% of differences) fell within various quality goals after correcting for inherent bias. Results: Only 7 of 14 analytes on the Heska analyzer and 2 analytes on the IDEXX analyzer attained the most stringent LOA quality goal, which was being within desirable total error based on biologic variation (TE Conclusions: The performance of both POC biochemistry analyzers was variable compared with a commercial laboratory analyzer. Performance goals were only able to be attained after the bias for each analyzer was accounted for by offsetting the LOAs and quality goals set by the mean bias for each analyte on each analyzer. (© 2024 The Authors. Veterinary Clinical Pathology published by Wiley Periodicals LLC on behalf of American Society for Veterinary Clinical Pathology.) |
Databáze: | MEDLINE |
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