Quantitative Contrast Sensitivity Function and the Effect of Aging in Healthy Adult Eyes: A Normative Database.

Autor:	Choi H, Vingopoulos F, Razavi P, Garcia MD, Garg I, Rodriguez J, Finn M, Baldwin G, Romano F, Ding X, Bannerman A, Tracy J, Wescott H, Husain D, Kim LA, Vavvas DG, Miller JB
Jazyk:	angličtina
Zdroj:	Ophthalmic surgery, lasers & imaging retina [Ophthalmic Surg Lasers Imaging Retina] 2024 Apr; Vol. 55 (4), pp. 212-219. Date of Electronic Publication: 2024 Feb 01.
DOI:	10.3928/23258160-20240124-01
Abstrakt:	Background and Objective: We sought to establish normative quantitative contrast sensitivity function (qCSF) values in healthy adult eyes and investigate the effect of age on qCSF. Patients and Methods: Healthy eyes underwent qCSF testing (adaptive sensory technology) and Snellen's visual acuity (VA). Descriptive statistics and mixed-effects multivariable linear regressions were evaluated. Results: A total of 334 eyes (290 patients) with median age 61 years (range 21 to 88) had qCSF values as follows: area under the log contrast sensitivity function curve: 1.18; contrast acuity: 1.32; contrast sensitivity (CS) at 1 cycle per degree (cpd): 1.32; CS at 1.5 cpd: 1.37; CS at 3 cpd: 1.38; CS at 6 cpd: 1.20; CS at 12 cpd: 0.69; CS at 18 cpd: 0.22. Linear reductions in qCSF values per decade of age ranged from -0.02 to -0.07 vs 0.01 for visual acuity (VA). Age had a greater effect on the majority of qCSF values than VA (beta standardized regression coefficient ranged from -0.309 to -0.141 for qCSF values vs 0.177 for VA). Conclusions: We herein establish a normative database for qCSF and quantify the effect of age on qCSF values, adding evidence towards the validation of qCSF as a clinical endpoint. [ Ophthalmic Surg Lasers Imaging Retina 2024;55:212-219.] .
Databáze:	MEDLINE
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