Biphasic Peritoneal Mesothelioma Is a Rare Tumor and a Diagnostic Challenge: A Case Report.

Autor:	Subahi EA; Internal Medicine, Hamad Medical Corporation, Doha, QAT., Fadul A; Internal Medicine, Hamad Medical Corporation, Doha, QAT., Mohamed A; Internal Medicine, Hamad Medical Corporation, Doha, QAT., Alsayed A; Internal Medicine, Hamad Medical Corporation, Doha, QAT., Ali EA; Internal Medicine, One Brooklyn Health/Interfaith Medical Center, Brooklyn, USA., Sayed S; Psychiatry, Hamad Medical Corporation, Doha, QAT., Mustafa S; Internal Medicine, Hamad Medical Corporation, Doha, QAT., Wazwaz B; Pathology, Hamad Medical Corporation, Doha, QAT., Fadul MH; Faculty of Medicine, University of Khartoum, Khartoum, SDN.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2024 Jan 05; Vol. 16 (1), pp. e51725. Date of Electronic Publication: 2024 Jan 05 (Print Publication: 2024).
DOI:	10.7759/cureus.51725
Abstrakt:	Malignant peritoneal mesothelioma (MPM) is a rare subtype of mesothelioma. There are three main histological subtypes of mesothelioma: epithelioid, sarcomatoid, and biphasic (mixed). Risk factors include asbestos exposure, previous radiation, and some germline mutations. Treatment includes surgical resection of amenable tumors or cytoreductive surgery and hyperthermic intraperitoneal chemotherapy. We present a 34-year-old male who presented with weight loss, night sweats, and pleuritic chest pain and was found to have ascites with peritoneal nodularity on abdominal imaging. He had a history of tuberculosis contact, but no history of asbestos exposure. After a long challenging and interesting diagnostic process, he was subsequently diagnosed with biphasic MPM. The diagnostic challenge stems from not only the rarity of the tumor but also from the absence of risk factors, the unavailability of some special laboratory investigations, in addition to the potentially misleading effect of tuberculosis exposure history, a top differential diagnosis in the case. This is a case report of a really challenging and totally unexpected diagnosis of biphasic peritoneal mesothelioma in a patient with tuberculosis exposure, constitutional symptoms, but no history of asbestos exposure. It highlights the diagnostic process as well as the importance of early diagnosis to improve the overall survival of such malignancies. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2024, Subahi et al.)
Databáze:	MEDLINE
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