Functional magnetic resonance imaging (fMRI) as adjunct for planning laser interstitial thermal therapy (LITT) near eloquent structures.

Autor: Rifi Z; David Geffen School of Medicine, University of California, Los Angeles, USA.; Department of Neurosurgery, University of California, Los Angeles, USA., Harary M; Department of Neurosurgery, University of California, Los Angeles, USA., Walshaw PD; Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, USA., Frew AJ; Department of Neurosurgery, University of California, Los Angeles, USA.; Department of Radiology, University of California, Los Angeles, USA., Everson RG; Department of Neurosurgery, University of California, Los Angeles, USA., Fallah A; Department of Neurosurgery, University of California, Los Angeles, USA., Salamon N; Department of Radiology, University of California, Los Angeles, USA., Kim W; Department of Neurosurgery, University of California, Los Angeles, USA. wonkim@mednet.ucla.edu.
Jazyk: angličtina
Zdroj: Acta neurochirurgica [Acta Neurochir (Wien)] 2024 Feb 05; Vol. 166 (1), pp. 66. Date of Electronic Publication: 2024 Feb 05.
DOI: 10.1007/s00701-024-05970-x
Abstrakt: LITT is a minimally-invasive laser ablation technique used to treat a wide variety of intracranial lesions. Difficulties performing intraoperative mapping have limited its adoption for lesions in/near eloquent regions. In this institutional case series, we demonstrate the utility of fMRI-adjunct planning for LITT near language or motor areas. Six out of 7 patients proceeded with LITT after fMRI-based tractography determined adequate safety margins for ablation. All underwent successful ablation without new or worsening postoperative symptoms requiring adjuvant corticosteroids, including those with preexisting deficits. fMRI is an easily accessible adjunct which may potentially reduce chances of complications in LITT near eloquent structures.
(© 2024. The Author(s).)
Databáze: MEDLINE
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