Impact of COVID-19 quarantines on clozapine-induced constipation: Experience of utilizing a clozapine-induced constipation protocol at a state forensic psychiatric facility.
| Autor: | Gleisner BM; Clinical Operational Pharmacist, McLean Hospital, Belmont, Massachusettes., Deardorff OG; Clinical Pharmacy Manager, Department of Pharmacy, Fulton State Hospital, Fulton, Missouri., Liu Y; Clinical Operational Pharmacist, McLean Hospital, Belmont, Massachusettes.; Clinical Pharmacy Manager, Department of Pharmacy, Fulton State Hospital, Fulton, Missouri.; Clinical Pharmacist, Department of Pharmacy, Fulton State Hospital, Fulton, Missouri.; Clinical Pharmacist, Department of Pharmacy, Fulton State Hospital, Fulton, Missouri.; Professor Emeritus, Division of Pharmacy Practice and Administration, University of Missouri - Kansas City School of Pharmacy, Kansas City, Missouri.; Professor Emeritus, Department of Psychiatry, University of Missouri Health Care, Columbia, Missouri., Trout MG; Clinical Pharmacist, Department of Pharmacy, Fulton State Hospital, Fulton, Missouri., Wood JR; Clinical Pharmacist, Department of Pharmacy, Fulton State Hospital, Fulton, Missouri., Sommi RW; Professor Emeritus, Division of Pharmacy Practice and Administration, University of Missouri - Kansas City School of Pharmacy, Kansas City, Missouri., Beck NC; Professor Emeritus, Department of Psychiatry, University of Missouri Health Care, Columbia, Missouri. |
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| Jazyk: | angličtina |
| Zdroj: | The mental health clinician [Ment Health Clin] 2024 Feb 01; Vol. 14 (1), pp. 68-72. Date of Electronic Publication: 2024 Feb 01 (Print Publication: 2024). |
| DOI: | 10.9740/mhc.2024.02.068 |
| Abstrakt: | Objective: Since 2017, Fulton State Hospital (FSH) has implemented a clozapine-induced constipation protocol. In March 2020, FSH initiated unit quarantines to minimize the spread of coronavirus disease (COVID-19). The objective of this study was to evaluate the impact of these quarantines on medical referrals for constipation, the Bristol Stool Chart ratings, utilization of as-needed (PRN) laxatives, and adherence rates with scheduled constipation medication regimens. Methods: Patients on the clozapine-induced constipation protocol from May 1, 2019 to December 31, 2020, were included, with 10-month pre- and mid-quarantine implementation. Data collected included patient demographics, primary psychiatric diagnosis, and outcome variables. Descriptive statistics and paired t-tests were performed. Results: A total of 31 patients were included. Most were male (93.5%), with a median age of 40 years. The most common primary diagnosis was schizophrenia. Compared with the pre-quarantine implementation period, there were fewer medical referral contacts per person, less use of PRN laxatives, and slightly lower adherence rates to scheduled constipation medication regimens during the mid-quarantine implementation period. Conclusion: Compared with the pre-quarantine implementation period, there were fewer medical referrals per person during the mid-quarantine implementation period. Competing Interests: Disclosures: The authors have no conflicts of interest to disclose. (© 2024 AAPP. The Mental Health Clinician is a publication of the American Association of Psychiatric Pharmacists.) |
| Databáze: | MEDLINE |
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