Abdominal Closure With Reinforcing Suture Decreases Incisional Hernia Incidence After CRS/HIPEC.

Autor:	Wenzelberg C; Department of Surgery, Skane University Hospital Malmö Sweden and Department of Clinical Sciences Malmö, Lund University, Lund, Sweden., Petersson U; Department of Surgery, Skane University Hospital Malmö Sweden and Department of Clinical Sciences Malmö, Lund University, Lund, Sweden., Syk I; Department of Surgery, Skane University Hospital Malmö Sweden and Department of Clinical Sciences Malmö, Lund University, Lund, Sweden., Ekberg O; Department of Radiology Diagnostics, Skane University Hospital Malmö Sweden and Department of Translational Medicine Malmö, Lund University, Lund, Sweden., Rogmark P; Department of Surgery, Skane University Hospital Malmö Sweden and Department of Clinical Sciences Malmö, Lund University, Lund, Sweden.
Jazyk:	angličtina
Zdroj:	Journal of abdominal wall surgery : JAWS [J Abdom Wall Surg] 2023 Mar 09; Vol. 2, pp. 11188. Date of Electronic Publication: 2023 Mar 09 (Print Publication: 2023).
DOI:	10.3389/jaws.2023.11188
Abstrakt:	Background: Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) entails several risk factors for incisional hernia (IH). A few reports available showing incidences between 7% and 17%. At our institution fascia closure has been performed in a 4:1 suture to wound length manner, with a continuous 2-0 polydiaxanone suture (PDS-group) or with a 2-0 polypropylene suture preceded by a reinforced tension line (RTL) suture (RTL-group). Our hypothesis was that these patients might benefit from reinforcing the suture line with a lower IH incidence in this group. The aim was to evaluate the 1-year IH-incidence of the two different closures. Methods: Patients eligible for inclusion were treated with CRS/HIPEC between 2004 and 2019. IH was diagnosed by scrutinizing CT-scans 1 year ±3 months after surgery. Additional data was retrieved from clinical records and a prospective CRS/HIPEC-database. Results: Of 193 patients, 129 were included, 82 in the PDS- and 47 in the RTL-group. RTL-patients were 5 years younger, had less blood loss and more frequent postoperative neutropenia. No difference regarding sex, BMI, recent midline incisions, excision of midline scars, peritoneal cancer index score, complications (≥Clavien-Dindo 3b), or chemotherapy. Ten IH (7.8%) were found, 9 (11%) in the PDS- and 1 (2.1%) in the RTL-group ( p = 0.071). Conclusion: An IH incidence of 7.8% in patients undergoing CRS/HIPEC is not higher than after laparotomies in general. The IH incidence in the PDS-group was 11% compared to 2% in the RTL-group. Even though significance was not reached, the difference is clinically relevant, suggesting an advantage with RTL suture. Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. (Copyright © 2023 Wenzelberg, Petersson, Syk, Ekberg and Rogmark.)
Databáze:	MEDLINE
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