| Autor: |
Zakharova PA; Moscow Regional Research and Clinical Institute named after M.F. Vladimirsky., Ilovayskaya IA; Moscow Regional Research and Clinical Institute named after M.F. Vladimirsky., Terpigorev SA; National Medical and Surgical Center named after N.I. Pirogov., Komerdus IV; Moscow Regional Research and Clinical Institute named after M.F. Vladimirsky., Lugovskaya AY; Moscow Regional Research and Clinical Institute named after M.F. Vladimirsky. |
| Jazyk: |
ruština |
| Zdroj: |
Problemy endokrinologii [Probl Endokrinol (Mosk)] 2024 Jan 24; Vol. 69 (6), pp. 47-53. Date of Electronic Publication: 2024 Jan 24. |
| DOI: |
10.14341/probl13203 |
| Abstrakt: |
Cushing's disease is a rare severe neuroendocrine disorder caused by chronic overproduction of adrenocorticotropic hormone by a pituitary tumor. Supraphysiological concentrations of cortisol in endogenous hypercortisolism have an immunosuppressive and anti-inflammatory effect similar to therapy with systemic glucocorticosteroids. This may reduce the activity of the patient's concomitant autoimmune inflammatory diseases. On the other hand, a decrease in cortisol levels during treatment for Cushing's disease may be associated with a reactivation of the immune system that pose a risk of onset or recurrence of an autoimmune disorder. We present our own clinical case demonstrating the development of sarcoidosis after surgical treatment of Cushing's disease. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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