Effect of Christmas Holidays on Type 1 Diabetes Mellitus in Users of Glucose Flash Systems.

Autor:	Sebastian-Valles F; Department of Endocrinology and Nutrition, Hospital Universitario de La Princesa, Instituto de Investigación Sanitaria de La Princesa, Universidad Autónoma de Madrid, Madrid, Spain. Electronic address: fernando.sebastian@estudiante.uam.es., Arranz Martin JA; Department of Endocrinology and Nutrition, Hospital Universitario de La Princesa, Instituto de Investigación Sanitaria de La Princesa, Universidad Autónoma de Madrid, Madrid, Spain., Martínez-Alfonso J; Department of Family and Community Medicine, Hospital La Princesa/Centro de Salud Daroca, Madrid, Spain., Jiménez-Díaz J; Department of Endocrinology and Nutrition, Hospital Universitario Severo Ochoa, Leganés, Madrid, Spain., Hernando Alday I; Department of Endocrinology and Nutrition, Hospital Universitario Basurto, Bilbao, Spain., Navas Moreno V; Department of Endocrinology and Nutrition, Hospital Universitario de La Princesa, Instituto de Investigación Sanitaria de La Princesa, Universidad Autónoma de Madrid, Madrid, Spain., Armenta Joya T; Department of Endocrinology and Nutrition, Hospital Universitario de La Princesa, Instituto de Investigación Sanitaria de La Princesa, Universidad Autónoma de Madrid, Madrid, Spain., Fandiño García MDM; Department of Endocrinology and Nutrition, Hospital Universitario Severo Ochoa, Leganés, Madrid, Spain., Román Gómez GL; Department of Endocrinology and Nutrition, Hospital Universitario Severo Ochoa, Leganés, Madrid, Spain., Garai Hierro J; Department of Endocrinology and Nutrition, Hospital Universitario Basurto, Bilbao, Spain., Lander Lobariñas LE; Department of Endocrinology and Nutrition, Hospital Universitario Severo Ochoa, Leganés, Madrid, Spain., Martinez de Icaya P; Department of Endocrinology and Nutrition, Hospital Universitario Severo Ochoa, Leganés, Madrid, Spain., Sampedro-Nuñez MA; Department of Endocrinology and Nutrition, Hospital Universitario de La Princesa, Instituto de Investigación Sanitaria de La Princesa, Universidad Autónoma de Madrid, Madrid, Spain., Martínez-Vizcaíno V; Health and Social Care Research Center, Universidad de Castilla-La Mancha, Cuenca, Spain; Facultad de Ciencias de la Salud, Universidad Autónoma de Chile, Talca, Chile., Marazuela M; Department of Endocrinology and Nutrition, Hospital Universitario de La Princesa, Instituto de Investigación Sanitaria de La Princesa, Universidad Autónoma de Madrid, Madrid, Spain.
Jazyk:	angličtina
Zdroj:	Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists [Endocr Pract] 2024 Apr; Vol. 30 (4), pp. 372-379. Date of Electronic Publication: 2024 Feb 01.
DOI:	10.1016/j.eprac.2024.01.011
Abstrakt:	Objective: Christmas holidays can impact weight and glycemic control in type 2 diabetes, but their effect on type 1 diabetes (T1D) remains understudied. This study assessed how Christmas holidays affect individuals with T1D who use flash continuous glucose monitoring systems. Methods: This retrospective study involved 812 adults diagnosed with T1D recruited from 3 hospitals. Clinical, anthropometric, and socioeconomic data were collected. Glucose metrics from 14 days before January 1st, and before December 1st and February 1st as control periods, were recorded. Analyses adjusted for multiple variables were conducted to assess the holiday season's impact on glycemic control. Results: The average time in range during the holidays (60.0 ± 17.2%) was lower compared to December (61.9 ± 17.2%, P < .001) and February (61.7 ± 17.7%, P < .001). Time above range (TAR > 180 mg/dL) was higher during Christmas (35.8 ± 18.2%) compared to December (34.1 ± 18.3%, P < .001) and February (34.2 ± 18.4%, P < .001). Differences were also observed in TAR >250 mg/dL, coefficient of variation, and average glucose (P < .05). No differences were found in time below range or other metrics. Linear regression models showed that the holidays reduced time in range by 1.9% (β = -1.92, P = .005) and increased TAR >180 mg/dL by 1.8% (β = 1.75, P = .016). Conclusion: Christmas holidays are associated with a mild and reversible deterioration in glucose metrics among individuals with T1D using flash continuous glucose monitoring, irrespective of additional influencing factors. These discoveries can be useful to advise individuals with diabetes during the festive season and to recognize potential biases within studies conducted during this timeframe. Competing Interests: Disclosure The authors have no conflicts of interest to disclose. (Copyright © 2024 AACE. Published by Elsevier Inc. All rights reserved.)
Databáze:	MEDLINE
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