Metformin and lamotrigine sorption on a digestate amended soil in presence of trace metal contamination.

Autor: Baldasso V; CIIMAR, Interdisciplinary Centre of Marine and Environmental Research, University of Porto, Portugal; Chemistry and Biochemistry Department, Faculty of Sciences, University of Porto, Porto, Portugal; Molecular Chemistry Institute of Reims, ICMR UMR CNRS 7312, University of Reims Champagne-Ardenne, Reims, France. Electronic address: veronica.baldasso@fc.up.pt., Sayen S; Molecular Chemistry Institute of Reims, ICMR UMR CNRS 7312, University of Reims Champagne-Ardenne, Reims, France. Electronic address: stephanie.sayen@univ-reims.fr., Gomes CAR; CIIMAR, Interdisciplinary Centre of Marine and Environmental Research, University of Porto, Portugal; Chemistry and Biochemistry Department, Faculty of Sciences, University of Porto, Porto, Portugal., Frunzo L; Department of Mathematics and Applications Renato Caccioppoli, University of Naples Federico II, Napoli, Italy., Almeida CMR; CIIMAR, Interdisciplinary Centre of Marine and Environmental Research, University of Porto, Portugal; Chemistry and Biochemistry Department, Faculty of Sciences, University of Porto, Porto, Portugal., Guillon E; Molecular Chemistry Institute of Reims, ICMR UMR CNRS 7312, University of Reims Champagne-Ardenne, Reims, France.
Jazyk: angličtina
Zdroj: Journal of hazardous materials [J Hazard Mater] 2024 Mar 15; Vol. 466, pp. 133635. Date of Electronic Publication: 2024 Jan 28.
DOI: 10.1016/j.jhazmat.2024.133635
Abstrakt: The antidiabetic drug metformin and antiepileptic drug lamotrigine are contaminants of emerging concern that have been detected in biowaste-derived amendments and in the environment, and their fate must be carefully studied. This work aimed to evaluate their sorption behaviour on soil upon digestate application. Experiments were conducted on soil and digestate-amended soil as a function of time to study kinetic processes, and at equilibrium also regarding the influence of trace metals (Pb, Ni, Cr, Co, Cu, Zn) at ratio pharmaceutical/metal 1/1, 1/10, and 1/100. Pharmaceutical desorption experiments were also conducted to assess their potential mobility to groundwater. Results revealed that digestate amendment increased metformin and lamotrigine adsorbed amounts by 210% and 240%, respectively, increasing organic matter content. Metformin adsorption kinetics were best described by Langmuir model and those of lamotrigine by Elovich and intraparticle diffusion models. Trace metals did not significantly affect the adsorption of metformin in amended soil while significantly decreased that of lamotrigine by 12-39%, with exception for Cu 2+ that increased both pharmaceuticals adsorbed amounts by 5 - 8%. This study highlighted the influence of digestate amendment on pharmaceutical adsorption and fate in soil, which must be considered in the circular economy scenario of waste-to-resource.
Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024 The Authors. Published by Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
Externí odkaz: