When mind and measurement diverge; the interplay between subjective cognitive complaints (SCCs), objective cognition, age, and depression in autistic adults.

Autor: Torenvliet C; Department of Psychology, Dutch Autism & ADHD Research Center, University of Amsterdam, Amsterdam, The Netherlands. Electronic address: c.torenvliet@uva.nl., Groenman AP; Department of Psychology, Dutch Autism & ADHD Research Center, University of Amsterdam, Amsterdam, The Netherlands; Research Institute of Child Development and Education, University of Amsterdam, The Netherlands; Department of Child and Adolescent Psychiatry Groningen, University of Groningen, University Medical Center Groningen, The Netherlands; Accare Child Study Center, Groningen, The Netherlands., Agelink van Rentergem JA; Department of Psychology, Dutch Autism & ADHD Research Center, University of Amsterdam, Amsterdam, The Netherlands., Radhoe TA; Department of Psychology, Dutch Autism & ADHD Research Center, University of Amsterdam, Amsterdam, The Netherlands; Dr. Leo Kannerhuis, Autism Clinic (Youz/Parnassia Group), Amsterdam, The Netherlands., Geurts HM; Department of Psychology, Dutch Autism & ADHD Research Center, University of Amsterdam, Amsterdam, The Netherlands; Dr. Leo Kannerhuis, Autism Clinic (Youz/Parnassia Group), Amsterdam, The Netherlands.
Jazyk: angličtina
Zdroj: Psychiatry research [Psychiatry Res] 2024 Mar; Vol. 333, pp. 115759. Date of Electronic Publication: 2024 Jan 26.
DOI: 10.1016/j.psychres.2024.115759
Abstrakt: While the increased incidence of dementia and subjective cognitive complaints (SCCs) suggests that autistic adults may face cognitive challenges at older age, the extent to which SCCs predict (future) cognitive functioning remains uncertain. This uncertainty is complicated by associations with variables like depression. The current study aims to unravel the interplay of age, depression, cognitive performance, and SCCs in autism. Using a large cross-sectional cohort of autistic (n=202) and non-autistic adults (n=247), we analyzed associations of SCCs with age, depression, and cognitive performance across three domains (visual memory, verbal memory, and fluency). Results showed a strong significant association between depression and SCCs in both autistic and non-autistic adults. Cognitive performance was not significantly associated with SCCs, except for a (modest) association between visual memory performance and SCCs in autistic adults only. Follow-up regression tree analysis indicated that depression and being autistic were considerably more predictive of SCCs than objective cognitive performance. Age nor sex was significantly associated with SCCs. These findings indicate that self-reported cognitive functioning does not equal cognitive performance, and should be interpreted with care, especially in individuals with high rates of depression. Longitudinal investigations are needed to understand SCCs' role in dementia and cognitive health in autism.
Competing Interests: Declaration of competing interest None of the authors have competing interests relevant to the work to report.
(Copyright © 2024. Published by Elsevier B.V.)
Databáze: MEDLINE
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