ANCA-associated glomerulonephritis and lupus nephritis following COVID-19 vaccination: a case report and literature review.

Autor:	Campos MAG; Clinical Hospital of State University Júlio de Mesquita Filho, State University of São Paulo, Botucatu, São Paulo, Brazil., Valois TO; Divison of Nephrology, University Hospital of the Federal University of Maranhão, São Luís, Maranhão, Brazil., Magalhães LE; Clinical Hospital of State University Júlio de Mesquita Filho, State University of São Paulo, Botucatu, São Paulo, Brazil., Vasques LF; Faculty of Medicine, University of Taubate, Taubaté, São Paulo, Brazil., de Medeiros RG; Faculty of Medicine, University of Taubate, Taubaté, São Paulo, Brazil., Costa DMDN; Divison of Nephrology, Hospital das Clínicas, Federal University of Pernambuco, Recife, Pernambuco, Brazil.; Recife Medical School, Federal University of Pernambuco, Recife, Pernambuco, Brazil., Salgado Filho N; Clinical Hospital of State University Júlio de Mesquita Filho, State University of São Paulo, Botucatu, São Paulo, Brazil., Nogueira RMDR; Faculty of Medicine, CEUMA University, São Luís, Maranhão, Brazil., Neves PDMM; Divison of Nephrology and Molecular Medicine, University of São Paulo, São Paulo, São Paulo, Brazil., Silva GEB; Clinical Hospital of State University Júlio de Mesquita Filho, State University of São Paulo, Botucatu, São Paulo, Brazil.; Department of Pathology and Legal Medicine, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil.
Jazyk:	angličtina
Zdroj:	Frontiers in immunology [Front Immunol] 2024 Jan 08; Vol. 14, pp. 1298622. Date of Electronic Publication: 2024 Jan 08 (Print Publication: 2023).
DOI:	10.3389/fimmu.2023.1298622
Abstrakt:	With the coverage of COVID-19 vaccination, it has been possible to observe the potential side effects of SARS-CoV-2 vaccines, with the most common ones being fever, myalgia, headache, and fatigue. However, an association has been observed between new and recurrent kidney injuries, mainly glomerulonephritis and lupus nephritis associated with ANCA, with the Pfizer-BioNTech, Moderna, Sinovac, and AstraZeneca vaccines, although the relationship between them is not clear. We report a case of ANCA-related vasculitis and lupus glomerulonephritis after the second dose of the AstraZeneca vaccine. The elderly patient presented significant worsening of kidney function after immunosuppression and complications after a new onset COVID-19 infection that led to death. We provide a literature review about kidney damage related to ANCA vasculitis after COVID-19 vaccine, aiming for a better understanding of the pathophysiological mechanism of kidney injury, its presentation, and treatment. Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. (Copyright © 2024 Campos, Valois, Magalhães, Vasques, de Medeiros, Costa, Salgado Filho, Nogueira, Neves and Silva.)
Databáze:	MEDLINE
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