Progress in mechanism-based diagnosis and treatment of tuberculosis comorbid with tumor.
Autor: | Wang C; School of Public Health, Kunming Medical University, Kunming, China., Zou RQ; Vice Director of Center of Sports Injury Prevention, Treatment and Rehabilitation China National Institute of Sports Medicine A2 Pangmen, Beijing, China., He GZ; School of Public Health, Kunming Medical University, Kunming, China. |
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Jazyk: | angličtina |
Zdroj: | Frontiers in immunology [Front Immunol] 2024 Jan 17; Vol. 15, pp. 1344821. Date of Electronic Publication: 2024 Jan 17 (Print Publication: 2024). |
DOI: | 10.3389/fimmu.2024.1344821 |
Abstrakt: | Tuberculosis (TB) and tumor, with similarities in immune response and pathogenesis, are diseases that are prone to produce autoimmune stress response to the host immune system. With a symbiotic relationship between the two, TB can facilitate the occurrence and development of tumors, while tumor causes TB reactivation. In this review, we systematically sorted out the incidence trends and influencing factors of TB and tumor, focusing on the potential pathogenesis of TB and tumor, to provide a pathway for the co-pathogenesis of TB comorbid with tumor (TCWT). Based on this, we summarized the latest progress in the diagnosis and treatment of TCWT, and provided ideas for further exploration of clinical trials and new drug development of TCWT. Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. (Copyright © 2024 Wang, Zou and He.) |
Databáze: | MEDLINE |
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