| Autor: |
Nam DY; College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University, Jeju, Korea., Jang SH; 24-Withheal Animal Medical Center, Gyeonggi-do, Korea., Yim SJ; College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University, Jeju, Korea., Kim JH; College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University, Jeju, Korea., Jung JY; College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University, Jeju, Korea. |
| Jazyk: |
angličtina |
| Zdroj: |
The Journal of veterinary medical science [J Vet Med Sci] 2024 Mar 16; Vol. 86 (3), pp. 312-316. Date of Electronic Publication: 2024 Jan 31. |
| DOI: |
10.1292/jvms.23-0385 |
| Abstrakt: |
A 12-year-old castrated male poodle presented with vomiting and diarrhea. Ultrasonography and computed tomography revealed a protruding mass at the caudal pole of the left kidney. Grossly, the poorly circumscribed abnormal mass was 1.6 × 1.8 × 1.9 cm in size and had multifocal dark-red foci. Microscopically, it was composed of densely or loosely packed variable-sized short spindle or ovoid cells. These neoplastic cells showed high pleomorphism, mitotic figures, and invasive tendency to the adjacent tissue. Immunohistochemically, the neoplastic spindle cells expressed vimentin, S100, neuron-specific enolase, nerve growth factor receptor, and laminin. Therefore, the mass was diagnosed as a malignant peripheral nerve sheath tumor (MPNST). To our knowledge, this is the first report of primary renal MPNST in a dog. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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