Quantitative determination of the binding capabilities of individual large-ring cyclodextrins in complex mixtures.
| Autor: | Larsen D; Department of Chemistry, Technical University of Denmark, Kemitorvet 207, DK-2800 Kongens Lyngby, Denmark. sopbee@kemi.dtu.dk., Erichsen A; Department of Chemistry, Technical University of Denmark, Kemitorvet 207, DK-2800 Kongens Lyngby, Denmark. sopbee@kemi.dtu.dk., Masciotta G; Department of Chemistry, Technical University of Denmark, Kemitorvet 207, DK-2800 Kongens Lyngby, Denmark. sopbee@kemi.dtu.dk., Meier S; Department of Chemistry, Technical University of Denmark, Kemitorvet 207, DK-2800 Kongens Lyngby, Denmark. sopbee@kemi.dtu.dk., Beeren SR; Department of Chemistry, Technical University of Denmark, Kemitorvet 207, DK-2800 Kongens Lyngby, Denmark. sopbee@kemi.dtu.dk. |
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| Jazyk: | angličtina |
| Zdroj: | Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2024 Feb 15; Vol. 60 (15), pp. 2090-2093. Date of Electronic Publication: 2024 Feb 15. |
| DOI: | 10.1039/d3cc05897b |
| Abstrakt: | Large-ring cyclodextrins (CDs) are a comparatively unexplored family of macrocycles. We use high-resolution 1 H- 13 C HSQC NMR experiments to resolve the anomeric signals of at least 13 different size CDs in a mixture. Using a single titration experiment, we can quantify the individual binding capabilites of these structurally-related hosts, avoiding the need for cumbersome isolation. |
| Databáze: | MEDLINE |
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