Evaluation of a Pharmacist-Led Implementation of Standardized Medication Administration Times for Inpatients Receiving Hemodialysis.

Autor:	Blunier AL; Department of Pharmacy, Eskenazi Health, Indianapolis, IN, USA.; Prisma Health Richland Hospital, Columbia, SC, USA., Cheatham MR; Department of Pharmacy, Eskenazi Health, Indianapolis, IN, USA., Deodhar KS; Department of Pharmacy, Eskenazi Health, Indianapolis, IN, USA., Geik CA; Department of Pharmacy, Eskenazi Health, Indianapolis, IN, USA., Walroth TA; Department of Pharmacy, Eskenazi Health, Indianapolis, IN, USA., Whitten JA; Department of Pharmacy, Eskenazi Health, Indianapolis, IN, USA., Davis CM; Department of Pharmacy, Eskenazi Health, Indianapolis, IN, USA.
Jazyk:	angličtina
Zdroj:	The Annals of pharmacotherapy [Ann Pharmacother] 2024 Oct; Vol. 58 (10), pp. 1027-1033. Date of Electronic Publication: 2024 Jan 31.
DOI:	10.1177/10600280231220079
Abstrakt:	Background: Missed medication doses are a common and often preventable medication-related error that have been associated with an increased length of stay and mortality. Hemodialysis is a common, relatively predictable reason that patients are unavailable, resulting in missed doses. Objective: To evaluate the implications of a pharmacist-led intervention to standardize the medication administration times for patients requiring hemodialysis who were prescribed antihypertensives, antiepileptics, apixaban, and/or antimicrobials. Methods: A retrospective preanalysis and postanalysis of a pharmacist-led intervention were performed at a single-center, safety net hospital. Patients receiving dialysis and prescribed one of the targeted medications were included. The primary endpoint was the composite of missed and delayed doses. Results: A total of 25 patients receiving 126 dialysis sessions in the preintervention group and 29 patients receiving 80 dialysis sessions in the postintervention group were included for analysis. For the primary endpoint, 118 (18%) versus 57 (9.3%) doses were missed or delayed in the preintervention versus postintervention group, respectively ( P < 0.001). The primary endpoint was driven by fewer delayed doses in the postgroup. The number of antimicrobials given on a correct schedule increased in the postintervention group (98.3% vs 99.1%, P = 0.044). Conclusion and Relevance: A pharmacist-led intervention for standard medication administration times in patients requiring hemodialysis increased the number of prescribed medication doses given and given on time. The intervention also led to more antimicrobials administered at appropriate times relative to dialysis sessions. Competing Interests: Declaration of Conflicting InterestsThe authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
Databáze:	MEDLINE
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