| Autor: |
Cui HJ; Department of Cardiac Surgery, Guangdong Provincial People's Hospital, Guangdong Cardiocvascular Diseases Institute, Guangzhou 510080, China., Chen JM; Department of Cardiac Surgery, Guangdong Provincial People's Hospital, Guangdong Cardiocvascular Diseases Institute, Guangzhou 510080, China., Wang SS; Department of Pediatric Cardiology, Guangdong Provincial People's Hospital, Guangdong Cardiocvascular Diseases Institute, Guangzhou 510080, China., Cen JZ; Department of Cardiac Surgery, Guangdong Provincial People's Hospital, Guangdong Cardiocvascular Diseases Institute, Guangzhou 510080, China., Xu G; Department of Cardiac Surgery, Guangdong Provincial People's Hospital, Guangdong Cardiocvascular Diseases Institute, Guangzhou 510080, China., Wen SS; Department of Cardiac Surgery, Guangdong Provincial People's Hospital, Guangdong Cardiocvascular Diseases Institute, Guangzhou 510080, China., Liu XB; Department of Cardiac Surgery, Guangdong Provincial People's Hospital, Guangdong Cardiocvascular Diseases Institute, Guangzhou 510080, China., Zhuang J; Department of Cardiac Surgery, Guangdong Provincial People's Hospital, Guangdong Cardiocvascular Diseases Institute, Guangzhou 510080, China. |
| Abstrakt: |
Objective: To analyze the diagnosis and surgical treatment of high-risk anomalous aortic origin of coronary artery (AAOCA). Methods: This is a retrospective case series study. From January 2016 to July 2023, 24 cases of high-risk AAOCA underwent surgical treatment in Department of Cardiac Surgery, Guangdong Provincial People's Hospital. There were 18 males and 6 females, operatively aged ( M (IQR)) 13 (26) years (range: 0.3 to 57.0 years). They were confirmed by cardiac ultrasound and cardiac CT, all of which had anomalous coronary running between the aorta and the pulmonary artery. There were 15 cases of the right coronary artery from the left aortic sinus of Valsalva, 6 cases of left coronary artery from the right aortic sinus of Valsalva, 3 cases of the sigle coronary artery. Only 3 patients had no obvious related symptoms (2 cases were complicated with a positive exercise stress test and 1 case with other intracardiac malformations), 21 cases had a history of chest tightness, chest pain, or syncope after exercise. Three patients suffered syncope after exercise and underwent cardiopulmonary resuscitation (2 cases were treated with an extracorporeal membrane oxygenerator (ECMO)). The gap from the first symptom to the diagnosis was 4.0 (11.5) months (range: 0.2 to 84.0 months). The detection rate of coronary artery abnormalities suggested by the first cardiac ultrasound was only 37.5% (9/24). Seven patients were complicated with other cardiac diseases (4 cases with congenital heart defects, 2 cases with coronary atherosclerotic heart disease, 1 case with mitral valve disease). Results: All 24 patients underwent surgical treatment (23 cases underwent abnormal coronary artery unroofing, 1 case underwent coronary artery bypass grafting), and 5 patients underwent other intracardiac malformation correction at the same time. There were no death or surgery related complications in the hospital for 30 days after the operation. A patient with preoperative extracorporeal cardiopulmonary resuscitation was continuously assisted by ECMO after emergency AAOCA correction and had complications such as limb ischemia necrosis and renal dysfunction after the operation. During the follow-up of 2.2 (3.3) years (range: 1 month to 7.2 years), one patient who previously underwent percutaneous transluminal coronary angioplasty with a stent implant experienced significant postoperative symptomatic relief, and the other discharged patients had no related symptoms. Conclusions: The accurate rate of initial diagnosis for high-risk AAOCA is still low, but the risk of cardiovascular accidents is high. For sports-related chest pain and other symptoms, more attention should be paid to the detection of AAOCA, especially for adolescents. Exercise stress testing can be helpful in evaluating the cardiovascular risk of asymptomatic AAOCA. Instant surgical treatment can achieve satisfactory curative effects. |
