The effect of tyrosine supplementation on whole-body endurance performance in physically active population: A systematic review and meta-analysis including GRADE qualification.

Autor: Solon-Júnior LJF; Department of Physical Education, Federal University of Paraíba, João Pessoa, Brazil., Boullosa Alvarez DA; Faculty of Physical Activity and Sports Sciences, Universidad de León, León, Spain.; Integrated Institute of Health, Federal University of Mato Grosso do Sul, Campo Grande, Brazil.; College of Healthcare Sciences, James Cook University, Townsville, Australia., Martinez Gonzalez B; Department for Life Quality Studies, University of Bologna, Rimini, Italy., da Silva Machado DG; Department of Physical Education, Federal University of Rio Grande do Norte, Natal, Brazil., de Lima-Junior D; Department for Life Quality Studies, University of Bologna, Rimini, Italy., de Sousa Fortes L; Department of Physical Education, Federal University of Paraíba, João Pessoa, Brazil.
Jazyk: angličtina
Zdroj: Journal of sports sciences [J Sports Sci] 2023 Nov; Vol. 41 (22), pp. 2045-2053. Date of Electronic Publication: 2024 Jan 30.
DOI: 10.1080/02640414.2024.2309434
Abstrakt: Although tyrosine supplementation is well recognized to improve cognitive function, its impact on endurance performance is debatable and needs to be clarified further. The purpose of this systematic review and meta-analysis was to evaluate the effects of tyrosine supplementation on whole-body endurance performance in physically active population. The search strategy follow the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA), using four databases (Cochrane Library, Web of Science, Scopus, PsycINFO, and PubMed) until 3 August 2023. The effect of tyrosine (experimental condition) was compared against placebo (control condition). The methodological quality of the included studies was evaluated using the Physiotherapy Evidence Database (PEDro) scale. The Grading of Recommendations Assessment, Development, and Evaluation (GRADE Pro software) System was also used to assess the quality of evidence. A total of 10 interventions from 8 studies were included. The sub-group analysis revealed no significant differences between tyrosine and placebo conditions for time to exhaustion (SMD = 0.02; p  = 0.94) and time trial performance (SMD = -0.04; p  = 0.85). The level of evidence as qualified with GRADE was moderate. In conclusion, moderate-quality evidence suggests that tyrosine supplementation is ineffective on endurance performance in the physically active population, independently of the endurance task (TTE or ETT).
Databáze: MEDLINE