Recent Advance of S100B Proteins in Spontaneous Intracerebral Hemorrhage and Aneurysmal Subarachnoid Hemorrhage.
| Autor: | Zhou ZM; Department of Neurosurgery, Dujiangyan Medical Center, 611800 Chengdu, Sichuan, China., Gu LL; Department of Anesthesiology, Dujiangyan Medical Center, 611800 Chengdu, Sichuan, China., Zhou ZY; Department of Medical Image Science, Shenyang Medical College, 110000 Shenyang, Liaoning, China., Liang QL; Department of Clinical Laboratory Medicine, Chongqing University Jiangjin Hospital, 402260 Chongqing, China. |
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| Jazyk: | angličtina |
| Zdroj: | Frontiers in bioscience (Landmark edition) [Front Biosci (Landmark Ed)] 2024 Jan 19; Vol. 29 (1), pp. 37. |
| DOI: | 10.31083/j.fbl2901037 |
| Abstrakt: | Human health is seriously endangered by spontaneous intracerebral hemorrhage (ICH) and aneurysmal subarachnoid hemorrhage (aSAH). Because the majority of ICH and aSAH survivors experience disability, increased risk of stroke recurrence, cognitive decline, and systemic vascular disease, ICH and aSAH assume special importance in neurological disease. Early detection and prediction of neurological function and understanding of etiology and correction are the basis of successful treatment. ICH and aSAH cause complex inflammatory cascades in the brain. In order to establish precise staging and prognosis, as well as provide a basis for treatment selection and monitoring, it is imperative to determine appropriate biological markers according to pathological and physiological mechanisms. In this review, we focus on the research progress of S100B, an endogenous danger signaling molecule, as a potential biomarker for ICH and aSAH, assisting in the development of further basic research and clinical translational studies. Competing Interests: The authors declare no conflict of interest. (© 2024 The Author(s). Published by IMR Press.) |
| Databáze: | MEDLINE |
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