A Case of Idiopathic Orbital Inflammation With Elevated Anti-Mumps Immunoglobulin M Antibody.
| Autor: | Han J; Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea., Woo KI |
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| Jazyk: | angličtina |
| Zdroj: | Ophthalmic plastic and reconstructive surgery [Ophthalmic Plast Reconstr Surg] 2024 May-Jun 01; Vol. 40 (3), pp. e86-e89. Date of Electronic Publication: 2024 Jan 25. |
| DOI: | 10.1097/IOP.0000000000002604 |
| Abstrakt: | A 21-year-old female presented with periocular swelling, diplopia, and painful ophthalmoplegia in the OS. Orbital magnetic resonance imaging revealed an enhanced soft tissue mass involving the left medial rectus muscle. Laboratory test results revealed leukocytosis, elevated reactive C-reactive protein, and positive serum levels of anti-mumps immunoglobulin M (IgM) antibody without systemic manifestations of mumps infection. The clinical course was refractory, and the patient showed a poor response to high-dose steroids. An incisional biopsy revealed stromal fibrosis with focal lymphoid aggregates, indicating sclerosing inflammation. Myopathy of the medial rectus progressed to superior, inferior, and lateral recti involvement of the left orbit. Immunosuppressive agents, including steroids, were administered for 22 months after disease onset. The mumps IgM antibody level was positive for over 5 months and became negative upon testing performed 1 year after the first visit. Competing Interests: The authors have no financial or conflicts of interest to disclose. (Copyright © 2024 The American Society of Ophthalmic Plastic and Reconstructive Surgery, Inc.) |
| Databáze: | MEDLINE |
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