Left atrial strain in adults after the arterial switch operation for transposition of the great arteries.

Autor: Buendía-Fuentes F; Cardiology Department, Hospital Universitari i Politecnic La Fe, Valencia, Spain.; Centro de Investigación Biomédica en Red en Enfermedades Cardiovasculares (CIBERCV), Madrid, Spain., Lozano-Edo S; Cardiology Department, Hospital Universitari i Politecnic La Fe, Valencia, Spain., Jover-Pastor P; Cardiology Department, Hospital Universitari i Politecnic La Fe, Valencia, Spain., Sánchez-Martínez JC; Cardiology Department, Hospital Universitari i Politecnic La Fe, Valencia, Spain., Martínez-Sole J; Cardiology Department, Hospital Universitari i Politecnic La Fe, Valencia, Spain., Rodríguez-Serrano M; Cardiology Department, Hospital Universitari i Politecnic La Fe, Valencia, Spain., Aguero J; Cardiology Department, Hospital Universitari i Politecnic La Fe, Valencia, Spain.; Centro de Investigación Biomédica en Red en Enfermedades Cardiovasculares (CIBERCV), Madrid, Spain., Arnau-Vives MA; Cardiology Department, Hospital Universitari i Politecnic La Fe, Valencia, Spain.; Centro de Investigación Biomédica en Red en Enfermedades Cardiovasculares (CIBERCV), Madrid, Spain., Osa-Sáez A; Cardiology Department, Hospital Universitari i Politecnic La Fe, Valencia, Spain.; Centro de Investigación Biomédica en Red en Enfermedades Cardiovasculares (CIBERCV), Madrid, Spain., Martínez-Dolz LV; Cardiology Department, Hospital Universitari i Politecnic La Fe, Valencia, Spain.; Centro de Investigación Biomédica en Red en Enfermedades Cardiovasculares (CIBERCV), Madrid, Spain., Rueda J; Cardiology Department, Hospital Universitari i Politecnic La Fe, Valencia, Spain.; Centro de Investigación Biomédica en Red en Enfermedades Cardiovasculares (CIBERCV), Madrid, Spain.
Jazyk: angličtina
Zdroj: Echocardiography (Mount Kisco, N.Y.) [Echocardiography] 2024 Jan; Vol. 41 (1), pp. e15750.
DOI: 10.1111/echo.15750
Abstrakt: Background: No study has focused on left atrial (LA) function assessed by echocardiography in adult patients with simple D-TGA after arterial switch operation (ASO). We aimed to describe LA strain parameters in these patients.
Methods: A prospective cohort study including 42 adult patients with simple D-TGA after ASO and 33 aged-matched controls. Phasic LA and LV global longitudinal strain (GLS) were obtained by transthoracic 2D-speckle tracking echocardiography (STE). Volumetric and functional analysis of LA and LV were also evaluated by 2D and 3D analysis. A multivariable model was performed to investigate the variables that best differentiate patients with D-TGA from healthy controls.
Results: LA strain parameters in D-TGA patients were within the normal range described for healthy subjects. However, the three LA strain parameters (Reservoir, Conduit, and Contraction) were lower in patients (LASr: 31.13 ± 7.67 vs. 49.71 ± 8.38; LAS cd: -22.91 ± 5.69 vs. -34.55 ± 6.54; LASct: -8.14 ± 4.93 vs. -15.15 ± 6.07, p < .001 for all three comparisons). LA volumes were similar between patients and controls. LV-GLS remained significantly lower in the D-TGA group than in controls (-17.29 ± 2.68 vs. -21.98 ± 1.84, p < .001). D-TGA patients had evidence of worse LV ejection fraction measured by the Teichholz method (63.38 ± 8.23 vs. 69.28 ± 5.92, p = .001) and 3D analysis (57.97% ± 4.16 vs. 60.67 ± 3.39, p = .011) and diastolic dysfunction as compared to healthy controls. LV-GLS and conduit LAS were the variables best differentiating patients with D-TGA from healthy controls.
Conclusions: LA strain is impaired in young adults with simple D-TGA late after the ASO, probably in agreement with some degree of LV dysfunction previously described.
(© 2024 Wiley Periodicals LLC.)
Databáze: MEDLINE
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