Single-Anastomosis Sleeve Jejunal Bypass as a Treatment for Morbid Obesity: A Systematic Review and Meta-Analysis.

Autor:	Alenezi MAM; Public Health Department, Maternity and Children Hospital-Arar, Ministry of Health, Arar, SAU., Alkhaldi SIH; Medical School, Faculty of Medicine, Northern Border University, Arar, SAU., Alrumaih YKI; Medical School, Faculty of Medicine, Northern Border University, Arar, SAU., Alzalabani AKM; Medical School, Faculty of Medicine, Northern Border University, Arar, SAU., Alnujaydi MAM; Medical School, Faculty of Medicine, Northern Border University, Arar, SAU., Alanazi SMF; Medical School, Faculty of Medicine, Northern Border University, Arar, SAU., Alotibi FAJ; Medical School, Faculty of Medicine, Northern Border University, Arar, SAU., Alanazi RZA; Medical School, Faculty of Medicine, Northern Border University, Arar, SAU., Alanazi MSM; Medical School, Faculty of Medicine, Northern Border University, Arar, SAU., Alanazi AAA; Medical School, Faculty of Medicine, University of Tabuk, Tabuk, SAU.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2023 Dec 29; Vol. 15 (12), pp. e51296. Date of Electronic Publication: 2023 Dec 29 (Print Publication: 2023).
DOI:	10.7759/cureus.51296
Abstrakt:	Single-anastomosis sleeve jejunal (SASJ) bypass is a bariatric surgery technique with promising results. However, evidence of its efficacy and safety is still lacking. This study aimed to summarize the evidence regarding the efficacy and safety of SASJ bypass surgery in the treatment of morbid obesity. The literature was searched for English-language studies published from inception till November 26, 2023, on MEDLINE/PubMed, Cochrane Library, Web of Science, ProQuest, Scopus, SCINAPSE, and Google Scholar. The search terms included "morbid obesity," "bariatric surgery," and "single anastomosis sleeve jejunal bypass." Extracted data included the body mass index (BMI) before and after surgery, percent total weight loss (%TWL), percent excess weight loss (%EWL), and improvement in preoperative comorbidities. Pooling of the data was done using random effects or fixed-effect models based on the presence of significant heterogeneity. Nine studies were included in this systematic review and meta-analysis. The change in BMI from baseline at 12 months after SASJ bypass was significant (standardized mean difference (SMD) = -3.576, 95% confidence interval (CI) = -5.423, -1.730; I² = 99.23%). At 12 months after surgery, the pooled %TWL was 42.526 (95% CI = 37.948, 47.105; I² = 97.15%), and the pooled %EWL was 75.258 (95% CI = 67.061, 83.456; I² = 99.26%). The pooled incidence of postoperative improvement in diabetes mellitus was 91% (95% CI = 79.6%, 98%, I² = 82%). The overall rate of complications was 9.9% (95% CI = 2.5%, 21.6%; I² = 92.64%). Regarding the short- and mid-term outcomes, SASJ bypass is a safe and effective procedure for weight loss in patients with morbid obesity, with an acceptable rate of complications. The procedure is also associated with a marked improvement in obesity-related comorbidities. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2023, Alenezi et al.)
Databáze:	MEDLINE
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